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This study investigated the phytochemical composition, antibacterial and antioxidant activities, and acute toxicity of ethanolic extracts from\n                    <jats:italic>Spondias mombin<\/jats:italic>\n                    L. and\n                    <jats:italic>Myracrodruon urundeuva<\/jats:italic>\n                    Allem\u00e3o. Extracts were analyzed by ultra\u2010performance liquid chromatography coupled with mass spectrometry (UPLC\u2013MS). Antibacterial activity was tested against\n                    <jats:italic>Vibrio parahaemolyticus<\/jats:italic>\n                    strains, whereas antioxidant activity was assessed using the DPPH assay. Acute toxicity was evaluated with\n                    <jats:italic>Artemia salina<\/jats:italic>\n                    nauplii. The\n                    <jats:italic>M. urundeuva<\/jats:italic>\n                    extract contained hydrolyzable tannins, gallic acid derivatives, anacardic acids, and agathisflavone, along with phenolic acids and dimeric chalcones, including urundeuvine B, in the stem bark. Only procyanidins were detected in\n                    <jats:italic>S. mombin<\/jats:italic>\n                    extracts. Both extracts exhibited moderate antibacterial activity and promising antioxidant potential, relevant for neutralizing oxidative bacterial defenses through scavenging of reactive oxygen species (ROS) and reactive nitrogen species (RNS), thereby supporting cellular redox homeostasis. The\n                    <jats:italic>M. urundeuva<\/jats:italic>\n                    extract showed the lowest minimum inhibitory concentration (MIC, 0.625\u20131.25\u00a0mg\/mL) and, together with\n                    <jats:italic>S. mombin<\/jats:italic>\n                    , demonstrated bactericidal activity surpassing ampicillin. Low acute toxicity was observed for both extracts (LC\n                    <jats:sub>50<\/jats:sub>\n                    \u00a0&gt;\u00a01000\u00a0\u00b5g\/mL), reinforcing their potential safety. These findings suggest that these plant extracts are promising natural alternatives for controlling\n                    <jats:italic>V. parahaemolyticus<\/jats:italic>\n                    in aquaculture systems.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202500534","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T17:23:24Z","timestamp":1753118604000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Phytochemical Composition and Evaluation of Acute Toxicity, Antioxidant, and Antibacterial Activities of\n                    <i>Spondias mombin<\/i>\n                    L. and\n                    <i>Myracrodruon urundeuva<\/i>\n                    Allem\u00e3o Ethanolic Extracts Against\n                    <i>Vibrio parahaemolyticus<\/i>"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5716-348X","authenticated-orcid":false,"given":"Luiz G. A.","family":"Santos\u2010Filho","sequence":"first","affiliation":[{"name":"Universidade Federal do Delta do Parna\u00edba, Laborat\u00f3rio de Biotecnologia e Aquicultura Marinha, Parna\u00edba, Piau\u00ed, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4595-7810","authenticated-orcid":false,"given":"Renata B.","family":"Reis","sequence":"additional","affiliation":[{"name":"Universidade Federal do Delta do Parna\u00edba, Laborat\u00f3rio de Mol\u00e9culas Vegetais, Parna\u00edba, Piau\u00ed, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1536-6588","authenticated-orcid":false,"given":"Ana Sheila Q.","family":"Souza","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3194-6125","authenticated-orcid":false,"given":"Kirley M.","family":"Canuto","sequence":"additional","affiliation":[{"name":"Embrapa Agroind\u00fastria Tropical  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5258-4015","authenticated-orcid":false,"given":"Paulo Riceli V.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Embrapa Agroind\u00fastria Tropical  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina N. C.","family":"Castro","sequence":"additional","affiliation":[{"name":"Embrapa Gado de Leite  Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0867-3552","authenticated-orcid":false,"given":"F\u00e1bio M.","family":"Diniz","sequence":"additional","affiliation":[{"name":"Embrapa Caprinos e Ovinos  Sobral Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alitiene M. 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