{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T02:44:12Z","timestamp":1784169852675,"version":"3.55.0"},"reference-count":62,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Medicinal plants have been extensively studied for their bioactive compounds and medicinal uses.\n                    <jats:italic>Dalbergia sissoo<\/jats:italic>\n                    , belonging to the Fabaceae family, has shown promise in traditional medicine for treating infections, cardiovascular diseases, and skin issues. However, systematic studies on its bioactive compounds and recovery efficiency using different solvents have been limited, particularly regarding potential industrial applications. This study aimed to conduct phytochemical screening and analyze the bioactivity of\n                    <jats:italic>D. sissoo<\/jats:italic>\n                    leaf extracts using ethanol, methanol, and distilled water as solvents. Chemical analyses were performed following standard protocols, including determining total phenolic content (TPC) via the Folin\u2010Ciocalteu assay, assessing total flavonoid content (TFC) through the aluminum chloride colorimetric method, identifying functional groups\n                    <jats:italic>via<\/jats:italic>\n                    Fourier\u2010transform infrared spectroscopy, and analyzing compounds using gas chromatography\u2010mass spectrometry. The study also evaluated antimicrobial and anticorrosive activity through agar well diffusion assays and electrochemical impedance spectroscopy. The ethanolic extract exhibited the highest level of bioactivity, displaying the broadest range of primary and secondary metabolites, including saponins, tannins, polysaccharides, terpenoids, glycosides, and amino acids. Compared to extracts obtained with methanol and distilled water, the ethanolic extract had the highest TPC of 42.39\u00a0mg gallic acid equivalent\/g and TFC of 39.31\u00a0mg quercetin equivalent\/g, along with superior antioxidant activity, as evidenced by the lowest IC\n                    <jats:sub>50<\/jats:sub>\n                    values (1,1\u2010diphenyl\u20102\u2010picrylhydrazyl: 562.21\u00a0\u00b5g\/mL, 2,2'\u2010azino\u2010bis(3\u2010ethylbenzothiazoline\u20106\u2010sulfonic acid): 225\u00a0\u00b5g\/mL). Antimicrobial screening experiments showed that the ethanolic extract produced the largest inhibition zones, particularly against\n                    <jats:italic>Klebsiella aerogenes<\/jats:italic>\n                    (16.26\u00a0mm) and\n                    <jats:italic>Micrococcus luteus<\/jats:italic>\n                    (18.8\u00a0mm) at a 60\u00a0mg\/mL concentration. It also demonstrated the highest corrosion inhibitory activity at 81.76% against a 1\u00a0M HCl solution, highlighting its potential for industrial application. The findings suggest that the\n                    <jats:italic>D. sissoo<\/jats:italic>\n                    ethanolic extract is a cost\u2010effective source rich in bioactive compounds with potential uses in both industrial and pharmaceutical fields. Future studies should focus on isolating and identifying the individual phenolic and flavonoid molecules responsible for the observed antimicrobial activity, particularly against\n                    <jats:italic>K. aerogenes<\/jats:italic>\n                    and\n                    <jats:italic>M. luteus<\/jats:italic>\n                    , as well as elucidating the molecular mechanisms involved in its corrosion inhibition for possible industrial applications.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202500602","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T03:38:57Z","timestamp":1745293137000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Dalbergia sissoo<\/i>\n                    Ethanolic Extract: A Natural Source of Antioxidant, Antibacterial, and Anticorrosive Agents"],"prefix":"10.1002","volume":"22","author":[{"given":"Deepali","family":"Deepali","sequence":"first","affiliation":[{"name":"Department of Botany Chaudhary Devi Lal University  Sirsa India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibhuti","family":"Gulia","sequence":"additional","affiliation":[{"name":"Department of Botany Chaudhary Devi Lal University  Sirsa India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Chemistry Chaudhary Devi Lal University  Sirsa India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6334-4642","authenticated-orcid":false,"given":"Jyoti","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Botany Chaudhary Devi Lal University  Sirsa India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukul Machhindra","family":"Barwant","sequence":"additional","affiliation":[{"name":"Department of Botany Sanjivani Arts, Commerce and Science College  Ahilyanagar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6598-4675","authenticated-orcid":false,"given":"Dinesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"School of Pharmacy Desh Bhagat University, Mandi  Gobindgarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxres\/tfaf011"},{"key":"e_1_2_11_3_1","volume-title":"Dalbergia sissoo","author":"Weng 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With Special Reference to Identification and Characterization of the Bioactive Principles","volume":"7","author":"Jose S.","year":"2022","journal-title":"International Journal of Novel Research and Development"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11426\u2010010\u20100122\u2010z"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2023.117640"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2023.110817"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.22271\/phyto.2023.v12.i1a.14557"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/sscp.202200079"},{"issue":"5","key":"e_1_2_11_39_1","first-page":"2175","article-title":"Chemical Analysis of Dalbergia sissoo (Roxb.) Pod Oil by (GC\u2010MS)\/GC\u2010FID and Evaluation of Antioxidant Potential","volume":"32","author":"Ali I.","year":"2019","journal-title":"Pakistan Journal of Pharmaceutical Sciences"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12161\u2010024\u201002594\u2010w"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.22206\/cac.2023.v6i2.3021"},{"key":"e_1_2_11_42_1","first-page":"43","volume-title":"Polyphenols in Human Health and Disease","author":"Dua A.","year":"2016"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1088\/1757\u2010899X\/991\/1\/012026"},{"issue":"3","key":"e_1_2_11_44_1","first-page":"429","article-title":"Antioxidant Capacities and Phytoconstituents of Fractions of Ethanol Extract of Cymbopogon citratus (DC.) Stapf: Inhibition of Iron II (Fe2\u207a)\u2010induced Lipid Peroxidation in Rat Colon Homogenate","volume":"23","author":"Karigidi M. 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Leaves","volume":"6","author":"Dwi H.","year":"2019","journal-title":"Research Journal of Life Science"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.53555\/sfs.v10i1s.817"},{"key":"e_1_2_11_50_1","volume-title":"FTIR Spectrum Analysis and Antimicrobial Activity of Roots and Leaves Extracts of Five Indian Medicinal Plants. In Proceedings of the 4th International Conference on Biological & Health Sciences (CIC\u2010BIOHS\u20192022)","author":"Khan W.","year":"2022"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foohum.2023.06.022"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.54607\/hcmue.js.19.7.3382"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268778"},{"issue":"8","key":"e_1_2_11_54_1","first-page":"459","article-title":"GC\u2010MS Analysis of Bioactive Compounds From Ethanolic Leaves Extract of Eichhornia crassipes (Mart.) Solms. 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