{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T18:53:31Z","timestamp":1787079211103,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Microbial metabolites serve as a vital source for drug discovery, with diphenyl ether derivatives from\n                    <jats:italic>Aspergillus<\/jats:italic>\n                    sp. garnering significant attention due to their antimicrobial activities. This work focused on the antibacterial compounds from the fungi\n                    <jats:italic>Aspergillus versicolor<\/jats:italic>\n                    YC\u201027, which led to the isolation of one new diphenyl ether derivative, aspesicol (\n                    <jats:bold>1<\/jats:bold>\n                    ), together with eight known compounds (\n                    <jats:bold>2<\/jats:bold>\n                    \u2013\n                    <jats:bold>9<\/jats:bold>\n                    ). The structure of the new compound was elucidated by spectroscopic methods, high\u2010resolution electrospray ionization mass spectrometry, and nuclear magnetic resonance calculations with DP4+ methods. In the in vitro bioassays, compounds\n                    <jats:bold>4<\/jats:bold>\n                    ,\n                    <jats:bold>5<\/jats:bold>\n                    , and\n                    <jats:bold>9<\/jats:bold>\n                    exhibited good inhibitory activity against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    with minimum inhibitory concentration (MIC) values of 8\u00a0\u00b5g\/mL, and compound\n                    <jats:bold>6<\/jats:bold>\n                    showed potent inhibitory activity against\n                    <jats:italic>S. aureus<\/jats:italic>\n                    with MIC value of 4\u00a0\u00b5g\/mL. These diphenyl ether derivatives demonstrating significant antimicrobial activity, particularly compound\n                    <jats:bold>6<\/jats:bold>\n                    , represent highly promising lead candidates for the development of therapeutic agents against multidrug\u2010resistant bacterial infections.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202500612","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T10:14:56Z","timestamp":1745489696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Antibacterial Diphenyl Ethers from Fungi\n                    <i>Aspergillus versicolor<\/i>\n                    YC\u201027"],"prefix":"10.1002","volume":"22","author":[{"given":"Geng","family":"Huang","sequence":"first","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&amp;D College of Pharmacy Dali University  Dali P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1702-7029","authenticated-orcid":false,"given":"Jia\u2010Peng","family":"Wang","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&amp;D College of Pharmacy Dali University  Dali P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui\u2010Lin","family":"He","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&amp;D College of Pharmacy Dali University  Dali P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&amp;D College of Pharmacy Dali University  Dali P. R. 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