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The fruit essential oil (FEO) with high content, representing a chemotype, was evaluated for pesticidal activities against three mosquito species <jats:italic>Aedes aegypti<\/jats:italic>, <jats:italic>Aedes albopictus<\/jats:italic>, and <jats:italic>Culex quinquefasciatus<\/jats:italic>, according to the WHO guidelines with modifications. The results showed that the major constituents of FEO were limonene (30.50%), sabinene (15.16%), terpinen\u20104\u2010ol (13.05%), and \u03b3\u2010terpinene (7.49%). The major constituents of leaf essential oil (LEO) were sabinene (20%), 1,8\u2010cineole (16.97%), limonene (12.32%), and 2\u2010undecanone (9.17%). The twig essential oil (TEO) was rich in ketones (73.84%), with the main constituents being 2\u2010undecanone (47.33%) and 2\u2010tridecanone (26.14%). FEO exhibited potential pesticidal activities: larvicidal activities with 24\u2010h LC<jats:sub>50<\/jats:sub> values ranging from 21.55 to 29.53\u00a0\u00b5g\/mL inhibited the biting of <jats:italic>A. aegypti<\/jats:italic> adults with a protection time of 176.5\u00a0\u00b1\u00a040.20\u00a0min, and exhibited potent adulticidal activities against <jats:italic>A. aegypti<\/jats:italic>. In addition, FEO did not exhibit cytotoxicity against the normal Vero cell line. This study contributes an evidence base to support the future development and use of FEO as a promising biopesticide agent for the control of disease\u2010transmitting mosquito species and altering synthetic pesticides.<\/jats:p>","DOI":"10.1002\/cbdv.202500648","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T13:11:06Z","timestamp":1745241066000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Chemical Composition and Pesticidal Activities Against Three Vector Mosquito Species of <i>Zanthoxylum armatum<\/i> DC. 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