{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T12:39:45Z","timestamp":1782131985072,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This study presents a novel and simplified method for generating lanthanum\u2010nitrogen\u2010enriched carbon dots (La\u2010NCDs) in a single step, using 2,2'\u2010(fumaroylbis(azanediyl))diacetic acid (FDG) as a starting material. The resulting lanthanum\u2010nitrogen\u2010carbon dots were carefully analyzed for their consistent structure, optical properties, and size, all of which indicated successful activation. The research then explored the antimicrobial potential of both La\u2010NCDs and FDG against common pathogens such as <jats:italic>Staphylococcus aureus, Escherichia coli<\/jats:italic>, and <jats:italic>Candida albicans<\/jats:italic>. La\u2010NCDs inhibit microbes greatly, demonstrating inhibition zones of up to 41\u00a0mm and minimum inhibitory concentrations (MICs) of 500\u20132000\u00a0\u00b5g\/mL depending on the microbe. In contrast, FDG displays weak antimicrobial activity. The 1,1\u2010diphenyl\u20102\u2010picrylhydrazyl\/2,2\u2010diphenyl\u20101\u2010picrylhydrazyl (DPPH) free radical scavenging assay was used to estimate the antioxidant properties of the materials. La\u2010NCDs were more efficient as antioxidants than FDG and inhibited free radicals with an IC<jats:sub>50<\/jats:sub> of 121.88\u00a0\u00b5g\/mL. This indicates that La\u2010NCDs antioxidants may find their place in biomedical applications concerning microbial infection and oxidative stress treatment.<\/jats:p>","DOI":"10.1002\/cbdv.202500745","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T19:00:47Z","timestamp":1748631647000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["One\u2010Pot Synthesis of Lanthanum\u2010Doped Carbon Dots From Fumaroyldiglycine With Antioxidant and Antimicrobial Activities"],"prefix":"10.1002","author":[{"given":"Peshawa Shafiq","family":"Osw","sequence":"first","affiliation":[{"name":"Department of Chemistry College of Science Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazha Omar","family":"Othman","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"},{"name":"Pharmacy Department Tishk International University  Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Kareem","family":"Samad","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Education Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebwar Muhammad","family":"Hamasalih","sequence":"additional","affiliation":[{"name":"Department of Biology College of Education Salahaddin University\u2010Erbil  Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Media Noori","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diyar Salahuddin","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"},{"name":"Department of Pharmacy College of Pharmacy Knowledge University  Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farouq Emam","family":"Hawaiz","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Education Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8885-8295","authenticated-orcid":false,"given":"Rebwar Omer","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science Salahaddin University\u2010Erbil  Erbil Kurdistan Region Iraq"},{"name":"Department of Radiological Imaging Technology College of Health Technology Cihan University\u2010Erbil  Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2jm34690g"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00112"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-014-0644-3"},{"issue":"1","key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"6371","DOI":"10.1038\/s41598-023-33652-8","article-title":"Green Synthesis of Multi\u2010Functional Carbon Dots From Medicinal Plant Leaves for Antimicrobial, Antioxidant, and Bioimaging Applications","volume":"13","author":"Gedda G.","year":"2023","journal-title":"Scientific Reports"},{"issue":"3","key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00604-023-05659-5","article-title":"Modified Lanthanide\u2010Doped Carbon Dots as a Novel Nanochemosensor for Efficient Detection of Water in Toluene and Its Potential Application in Lubricant Base Oils","volume":"190","author":"Chimeno\u2010Trinchet C.","year":"2023","journal-title":"Microchimica Acta"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c12408"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202400463"},{"issue":"11","key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11051-024-06180-3","article-title":"Enhancing Nanomedicine With Doped Carbon Quantum Dots: A Comprehensive Review","volume":"26","author":"Othman H. 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