{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:52:25Z","timestamp":1790952745620,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study presents the first comprehensive report on the phenolic composition, antioxidant activities, antimicrobial properties, and DNA protection potential of methanol and water extracts from flower parts of\n                    <jats:italic>Onopordum carduchorum<\/jats:italic>\n                    collected in the Gaziantep region of Turkey. In quantitative chromatographic analysis, bioactive compounds such as chlorogenic acid, 4\u2010hydroxybenzoic acid, syringic acid, pinoresinol, protocatechuic acid, caffeic acid, and apigenin were detected in both extracts, with a total of 22 phenolic compounds found. While the total phenolic content was higher in the aqueous extract (35.41\u00a0mg GAE\/g), the methanol extract showed a higher flavonoid content (13.80\u00a0mg RE\/g) (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). The aqueous extract exhibited significant antioxidant activity in DPPH, ABTS, FRAP, CUPRAC, metal chelation, and phosphomolybdenum tests, showing lower IC\n                    <jats:sub>50<\/jats:sub>\n                    and EC\n                    <jats:sub>50<\/jats:sub>\n                    values compared to the methanol extract (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). In contrast, the methanol extract showed relatively weaker antioxidant potential with higher IC\n                    <jats:sub>50<\/jats:sub>\n                    and EC\n                    <jats:sub>50<\/jats:sub>\n                    values in all analyses. Both extracts showed protective effects on DNA and provided significant protection against UV radiation. In contrast, no antimicrobial activity was observed against the tested strains. This study presents the first report on\n                    <jats:italic>O. carduchorum<\/jats:italic>\n                    flowers and provides baseline data to explore their phenolic profiles, antioxidant, and UV\u2010protective potential.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202500791","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:50:52Z","timestamp":1758383452000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phenolic Compounds, Antioxidant Capacity, and DNA\u2010Protective Properties of\n                    <i>Onopordum carduchorum<\/i>\n                    Flower Extracts"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6275-5067","authenticated-orcid":false,"given":"Feyza","family":"Da\u011fl\u0131","sequence":"first","affiliation":[{"name":"Department of Biology, Institute of Natural and Applied Sciences Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6477-6604","authenticated-orcid":false,"given":"Ali","family":"\u00c7apan","sequence":"additional","affiliation":[{"name":"Department of Food Processing Nizip Vocat\u0131onal H\u0131gh School, Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0272-5131","authenticated-orcid":false,"given":"\u0130brahim Halil","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Arts and Sciences Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22063009"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2018.02.397"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000355255"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants8020040"},{"issue":"1","key":"e_1_2_9_6_1","first-page":"8","article-title":"The Research of Antioxidant Activity of the Endemic Species of Onopordum anatolicum","volume":"1","author":"Tasdelen G.","year":"2014","journal-title":"International Journal of Secondary Metabolite"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201070463\u20107"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X1200700904"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/pr11102962"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejchem.2022.126845.5640"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/agronomy14050987"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.22037\/ijpr.2017.2129"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100032\u20101315259"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.9755\/ejfa.2016\u201005\u2010544"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0280464"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12668\u2010022\u201000970\u20106"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2017.09.008"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.692"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.energy.2022.125305"},{"key":"e_1_2_9_20_1","first-page":"89","article-title":"Ant\u0131ox\u0131dant Act\u0131v\u0131t\u0131es of Onopordum anatolicum Seeds","volume":"41","author":"Sarikurkcu C.","year":"2015","journal-title":"Selcuk University Faculty of Science Journal of Science"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578x1400900716"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13002\u2010019\u20100327\u2010y"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/geac006"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2020.06.015"},{"key":"e_1_2_9_25_1","first-page":"28","article-title":"Zahter (Thymbra spicata L. var. spicata) Investigation of DNA Protective Activities and Antimicrobial Effects of Plant Extracts on Stenotrophomonas maltophilia","volume":"1","author":"Joma M. 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