{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T19:08:54Z","timestamp":1775070534426,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study presents the first phytochemical analysis of the essential oils from the fresh leaves of\n                    <jats:italic>Loranthus tienyenensis<\/jats:italic>\n                    Li and\n                    <jats:italic>Planchonella obovata<\/jats:italic>\n                    (R. Br.) Pierre using gas chromatography\u2010mass spectrometry.\n                    <jats:italic>L. tienyenensis<\/jats:italic>\n                    essential oil was characterized by neryl isobutanoate (13.8%), linalool (10.8%), cis\u2010linalool oxide (6.5%), hexadecanoic acid (6.2%),\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010linalool oxide (5.6%), and\n                    <jats:italic>cis<\/jats:italic>\n                    \u2010phytol (5.5%).\n                    <jats:italic>P. obovata<\/jats:italic>\n                    essential oil was dominated by (\n                    <jats:italic>Z<\/jats:italic>\n                    ,\n                    <jats:italic>E<\/jats:italic>\n                    )\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010farnesene (13.7%) and (3\n                    <jats:italic>Z<\/jats:italic>\n                    )\u2010cembrene A (12.0%).\n                    <jats:italic>P. obovata<\/jats:italic>\n                    essential oil exhibited strong antimicrobial activity against Gram\u2010negative bacteria\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    , and the yeast\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    , with the same minimum inhibitory concentration of 32\u00a0\u00b5g\/mL. Both essential oils showed moderate larvicidal activity against third\u2010instar larvae of\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    ,\n                    <jats:italic>Ae. albopictus<\/jats:italic>\n                    , and\n                    <jats:italic>Culex quinquefasciatus<\/jats:italic>\n                    , with 24\u2010h lethal dose 50% values below 100\u00a0\u00b5g\/mL. Molecular docking revealed that (\n                    <jats:italic>Z<\/jats:italic>\n                    ,\n                    <jats:italic>E<\/jats:italic>\n                    )\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010farnesene interacted with bacterial proteins enoyl\u2010ACP reductase (FabI), dihydrofolate reductase (DHFR), and beta\u2010lactamase, while (3\n                    <jats:italic>Z<\/jats:italic>\n                    )\u2010cembrene A effectively targeted DHFR, DNA gyrase, and peptidoglycan transpeptidase.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501009","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T20:39:06Z","timestamp":1752179946000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Loranthus tienyenensis<\/i>\n                    Li and\n                    <i>Planchonella obovata<\/i>\n                    (R. Br.) Pierre: Essential Oil Composition, Biological Activity, and Molecular Docking"],"prefix":"10.1002","volume":"22","author":[{"given":"Ty Viet","family":"Pham","sequence":"first","affiliation":[{"name":"Faculty of Chemistry University of Education Hue University  Hue Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thao Xuan","family":"Hoang","sequence":"additional","affiliation":[{"name":"Faculty of Biology University of Education Hue University  Hue Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen Dinh","family":"Luyen","sequence":"additional","affiliation":[{"name":"Institute of Natural Products Chemistry Vietnam Academy of Science and Technology (VAST)  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pham Minh","family":"Quan","sequence":"additional","affiliation":[{"name":"Institute of Natural Products Chemistry Vietnam Academy of Science and Technology (VAST)  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen Huy","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Duy Tan University  Danang Vietnam"},{"name":"Center for Advanced Chemistry Institute of Research and Development Duy Tan University  Danang Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen Thanh","family":"Hao","sequence":"additional","affiliation":[{"name":"Faculty of Biotechnology Vietnam National University of Agriculture  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Huy","family":"Gioi","sequence":"additional","affiliation":[{"name":"Faculty of Biotechnology Vietnam National University of Agriculture  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen Ngoc","family":"Linh","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy Thanh Do University  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duong Anh","family":"Duy","sequence":"additional","affiliation":[{"name":"The Village School A Nord Anglia Education School  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2413-7496","authenticated-orcid":false,"given":"Ninh The","family":"Son","sequence":"additional","affiliation":[{"name":"Institute of Chemistry Vietnam Academy of Science and Technology (VAST)  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"655","article-title":"Evidence From Micromorphology and Gross Morphology of the Genus Loranthus (Loranthaceae) in Iran","volume":"36","author":"Shavvon R. 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