{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T21:46:31Z","timestamp":1781732791155,"version":"3.54.5"},"reference-count":60,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Cratoxylum formosum<\/jats:italic>\n                    (Jack) Benth. &amp; Hook.f. ex Dyer is a medicinal plant widely distributed in Southeast Asia. This study presents the first investigation of the essential oil from leaves of\n                    <jats:italic>C. formosum<\/jats:italic>\n                    collected in Vietnam, focusing on its chemical composition, antimicrobial activity, and mosquito larvicidal potential. Gas chromatography\u2013flame ionization detection (GC\u2013FID)\/mass spectrometry (MS) analysis identified 35 compounds in the essential oil, with (\n                    <jats:italic>E<\/jats:italic>\n                    )\u2010caryophyllene (39.30%), \u03b1\u2010humulene (12.90%), and (\n                    <jats:italic>E<\/jats:italic>\n                    )\u2010\u03b2\u2010ocimene (11.85%) as the major constituents. The essential oil exhibited notable antimicrobial activity against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    ,\n                    <jats:italic>Enterococcus faecalis<\/jats:italic>\n                    ,\n                    <jats:italic>Bacillus cereus<\/jats:italic>\n                    ,\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    , and\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    , with minimum inhibitory concentration (MIC) values ranging from 16 to 64\u00a0\u00b5g\/mL and IC\n                    <jats:sub>50<\/jats:sub>\n                    values between 7.55 and 20.56\u00a0\u00b5g\/mL. Larvicidal assays demonstrated strong activity against\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    ,\n                    <jats:italic>Aedes albopictus<\/jats:italic>\n                    , and\n                    <jats:italic>Culex quinquefasciatus<\/jats:italic>\n                    , with LC\n                    <jats:sub>50<\/jats:sub>\n                    values ranging from 44.27 to 77.71\u00a0\u00b5g\/mL and LC\n                    <jats:sub>90<\/jats:sub>\n                    values from 57.74 to 102.61\u00a0\u00b5g\/mL after 24 and 48\u00a0h of exposure. These findings suggest that\n                    <jats:italic>C. formosum<\/jats:italic>\n                    essential oil is a promising natural source of antimicrobial and mosquito control agents.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501348","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:28:33Z","timestamp":1770719313000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["First Report on the Chemical Profile and Biological Effects of the Essential Oil From\n                    <i>Cratoxylum formosum<\/i>\n                    (Jack) Benth. &amp; Hook.f. ex Dyer Collected in Vietnam"],"prefix":"10.1002","volume":"23","author":[{"given":"Le T.","family":"Huong","sequence":"first","affiliation":[{"name":"Faculty of Biology, College of Education Vinh University Vinh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do 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