{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:41:06Z","timestamp":1773013266806,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Twenty\u2010seven compounds were isolated from\n                    <jats:italic>Anaphalis hancockii<\/jats:italic>\n                    Maxim in Qinghai Province, China, including 7 isobenzofuranones (\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>7<\/jats:bold>\n                    ), 8 flavonoids (\n                    <jats:bold>8\u201315<\/jats:bold>\n                    ), and 12 other compounds (\n                    <jats:bold>16\u201327<\/jats:bold>\n                    ). Compound\n                    <jats:bold>1<\/jats:bold>\n                    is a new isobenzofuranone. The structures of the compounds were determined by analyzing their HRESIMS, 1D\u2010 and 2D\u2010nuclear magnetic resonance (NMR), electronic circular dichroism (ECD) and comparing them to the reported data. This study is the first report of\n                    <jats:italic>A. hancockii<\/jats:italic>\n                    Maxim's chemical composition, a perennial herb belonging to the genus\n                    <jats:italic>Anaphalis<\/jats:italic>\n                    . Isobenzofuranones are the main bioactive constituents of the genus\n                    <jats:italic>Anaphalis<\/jats:italic>\n                    ; thus, seven isobenzofuranones (\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>7<\/jats:bold>\n                    ) were assessed for their antibacterial and antichlamydial activities. Compound\n                    <jats:bold>6<\/jats:bold>\n                    showed moderate activity against six different pathogenic fungi. The result suggested that Compound\n                    <jats:bold>5<\/jats:bold>\n                    might be a promising class of therapeutic agents for chlamydial infections.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501379","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T18:08:51Z","timestamp":1753294131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chemical Constituents of\n                    <i>Anaphalis hancockii<\/i>\n                    Maxim"],"prefix":"10.1002","volume":"22","author":[{"given":"Guo\u2010Li","family":"Li","sequence":"first","affiliation":[{"name":"Research Institute, School of Chemistry and Chemical Engineering Lanzhou Jiaotong University  Lanzhou Gansu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Gong","sequence":"additional","affiliation":[{"name":"Research Institute, School of Chemistry and Chemical Engineering Lanzhou Jiaotong University  Lanzhou Gansu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010lin","family":"He","sequence":"additional","affiliation":[{"name":"Research Institute, School of Chemistry and Chemical Engineering Lanzhou Jiaotong University  Lanzhou Gansu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao\u2010Cai","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Animal Disease Control and Prevention Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences  Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-6554","authenticated-orcid":false,"given":"Tong","family":"Shen","sequence":"additional","affiliation":[{"name":"Research Institute, School of Chemistry and Chemical Engineering Lanzhou Jiaotong University  Lanzhou Gansu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,23]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Editorial Committee of Chinese flora of Chinese Academy of Sciences","author":"Flora of China","year":"1979"},{"key":"e_1_2_9_3_1","volume-title":"Jiangsu College of New Medicine. A Dictionary of Traditional Chinese Medicines","year":"1977"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1074547"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-016-1688-2"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2004.08.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.03.024"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-45222-y"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/pm.pm_546_16"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.01.004"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-022-07158-z"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2603.191417"},{"key":"e_1_2_9_13_1","first-page":"302","article-title":"Overview of Pathogen Causing Potato Fusarium wilt","volume":"31","author":"An X. M.","year":"2017","journal-title":"Chinese Potato Journal"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24112140"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11418-014-0877-1"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2017.10.019"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)81462-4"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2017.10.019"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-024-00720-8"},{"key":"e_1_2_9_20_1","first-page":"1185","article-title":"A New Furobenzopyranone From Anaphalis lactea","volume":"15","author":"Wang A. X.","year":"2004","journal-title":"Chinese Chemical Letters"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-024-00720-8"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100041\u2010111631"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-111631"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26206098"},{"key":"e_1_2_9_25_1","first-page":"91","article-title":"Studies on the Flavonoid Components of Abelmoschus manihot L. Medic","volume":"2","author":"Wang X. R.","year":"2004","journal-title":"Chinese Journal of Natural Medicines"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-020-03026-x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-011-0808-6"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(01)01109-1"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2023.104580"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-009-9359-1"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.112958"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0367-326X(00)00240-9"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/vjch.202100211"},{"key":"e_1_2_9_34_1","first-page":"54","article-title":"Study on Chemical Constituents of Euodia austrosinensis Hand Mazz and Their Anti Inflammatory Activity","volume":"35","author":"Li Y.","year":"2023","journal-title":"Natural Product Research and Development"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(95)00790-3"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2018.1437433"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2005.01.003"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-012-0120-0"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-021-02777-8"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010-016-2154-0"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.103535"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202501379","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202501379","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202501379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:23:14Z","timestamp":1773008594000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202501379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,23]]},"references-count":40,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/cbdv.202501379"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202501379","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,23]]},"assertion":[{"value":"2025-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01379"}}