{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:44:52Z","timestamp":1787237092173,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Natural products have long been regarded as an important source of lead compounds for innovative drugs due to their unique structural diversity and biological activities. The rhizomes of\n                    <jats:italic>Valeriana jatamansi<\/jats:italic>\n                    Jones (Valerianaceae), a plant incorporated in the Chinese materia medica, have been widely employed in southwestern China to treat diarrhoea, infections, and anxiety. To further explore its active ingredients, in the present study, a phytochemical investigations of\n                    <jats:italic>V. jatamansi<\/jats:italic>\n                    , resulted in the identification of a novel olivetolic acid analog, jatamanine (\n                    <jats:bold>1<\/jats:bold>\n                    ), accompanied by sixteen previously reported compounds (\n                    <jats:bold>2<\/jats:bold>\n                    \u2013\n                    <jats:bold>17<\/jats:bold>\n                    ):\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010sitosterol (\n                    <jats:bold>2<\/jats:bold>\n                    ),\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010sitostenone (\n                    <jats:bold>3<\/jats:bold>\n                    ), deacylbaldrinal (\n                    <jats:bold>4<\/jats:bold>\n                    ), 11\u2010ethoxyviburtinal (\n                    <jats:bold>5<\/jats:bold>\n                    ), baldrinal (\n                    <jats:bold>6<\/jats:bold>\n                    ), jatamanin A (\n                    <jats:bold>7<\/jats:bold>\n                    ), 1,5\u2010dihydroxy\u20103,8\u2010epoxyvalechlorine A (\n                    <jats:bold>8<\/jats:bold>\n                    ), chlorovaltrate A (\n                    <jats:bold>9<\/jats:bold>\n                    ), desoxidodidrovaltrate (\n                    <jats:bold>10<\/jats:bold>\n                    ), valeriananoid C (\n                    <jats:bold>11<\/jats:bold>\n                    ), vanillin (\n                    <jats:bold>12<\/jats:bold>\n                    ), vanillic acid (\n                    <jats:bold>13<\/jats:bold>\n                    ),\n                    <jats:italic>p<\/jats:italic>\n                    \u2010hydroxybenzaldehyde (\n                    <jats:bold>14<\/jats:bold>\n                    ), coniferaldehyde (\n                    <jats:bold>15<\/jats:bold>\n                    ), scopoletin (\n                    <jats:bold>16<\/jats:bold>\n                    ), and 3\u2010methyl\u20102\u2010(3\u2010methyl\u20101\u2010oxobutoxy)butanoic acid (\n                    <jats:bold>17<\/jats:bold>\n                    ). Structural elucidation was accomplished by detailed spectroscopic analysis. Compounds\n                    <jats:bold>1<\/jats:bold>\n                    ,\n                    <jats:bold>3<\/jats:bold>\n                    ,\n                    <jats:bold>12<\/jats:bold>\n                    ,\n                    <jats:bold>15<\/jats:bold>\n                    , and\n                    <jats:bold>17<\/jats:bold>\n                    were identified as unreported constituents of this plant. Significantly, the nuclear magnetic resonance spectral information of\n                    <jats:bold>17<\/jats:bold>\n                    is newly reported in this work. Antimicrobial screening results indicated that compound\n                    <jats:bold>1<\/jats:bold>\n                    possessed substantial inhibitory activity, exhibiting minimum inhibitory concentration values of 4\u00a0mg\/L against both\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    , while showing 8\u00a0mg\/L toward\n                    <jats:italic>Bacillus subtilis<\/jats:italic>\n                    and 16\u00a0mg\/L against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501667","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:49:47Z","timestamp":1758383387000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A New Phenolic Compound With Antimicrobial Activity From\n                    <i>Valeriana jatamansi<\/i>\n                    Jones"],"prefix":"10.1002","volume":"22","author":[{"given":"Liangrui","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry For Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology Yunnan University  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingquan","family":"Yang","sequence":"additional","affiliation":[{"name":"China Tobacco Yunnan Industry Co., Ltd.  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifu","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry For Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology Yunnan University  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengmei","family":"Zhang","sequence":"additional","affiliation":[{"name":"China Tobacco Yunnan Industry Co., Ltd.  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxin","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Agriculture Yunnan University  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry For Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology Yunnan University  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinong","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry For Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology Yunnan University  Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian\u2010Peng","family":"Yin","sequence":"additional","affiliation":[{"name":"Faculty of Bioengineering Zunyi Medical University  Zhuhai P. R. 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