{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T17:14:26Z","timestamp":1789838066155,"version":"4.0.1"},"reference-count":56,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Pistacia atlantica<\/jats:italic>\n                    and\n                    <jats:italic>Oudneya africana<\/jats:italic>\n                    are medicinal plants from arid Tunisian regions, traditionally used for their therapeutic properties. This study comparatively evaluated their ethanol and aqueous leaf extracts for phytochemical content and biological activities. LC\u2013ESI\u2013MS identified 19 bioactive compounds, including flavonoids and phenolic acids. The ethanolic extracts exhibited significantly higher total phenolic contents (119.80\u00a0\u00b1\u00a02.45\u00a0mg GAE\/g DW for\n                    <jats:italic>O. africana<\/jats:italic>\n                    vs. 110.14\u00a0\u00b1\u00a03.50\u00a0mg GAE\/g DW for\n                    <jats:italic>P. atlantica<\/jats:italic>\n                    ). Antioxidant assays revealed that\n                    <jats:italic>P. atlantica<\/jats:italic>\n                    aqueous extract exhibited the strongest DPPH and ABTS scavenging activities (IC\n                    <jats:sub>50<\/jats:sub>\n                    \u00a0=\u00a0113 and 8.96\u00a0\u00b5g\/mL, respectively), while\n                    <jats:italic>O. africana<\/jats:italic>\n                    ethanolic extract showed the highest ferric\u2010reducing power (EC\n                    <jats:sub>50<\/jats:sub>\n                    \u00a0=\u00a051.00\u00a0\u00b5g\/mL). Antimicrobial testing showed the ethanolic extracts had MIC values as low as 0.625\u00a0mg\/mL against\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    and\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    , indicating superior efficacy. Photoprotective analysis revealed\n                    <jats:italic>P. atlantica<\/jats:italic>\n                    ethanolic extract possessed a higher SPF (47.4) than\n                    <jats:italic>O. africana<\/jats:italic>\n                    (39.9), suggesting greater potential as a natural sunscreen agent. These comparative results highlight the advantages of ethanolic extraction for maximizing bioactive compound yield and biological effectiveness and emphasize\n                    <jats:italic>P. atlantica<\/jats:italic>\n                    's stronger potential in antioxidant and photoprotective applications compared to\n                    <jats:italic>O. africana<\/jats:italic>\n                    . This study underscores the value of both species as sources of natural bioactive compounds, with differential properties suited to various medicinal and cosmetic uses.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501781","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T22:09:21Z","timestamp":1753999761000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["HPLC\u2013ESI\/MS\u2010Based Polyphenolic Profiling and Bioactivities of\n                    <i>Pistacia atlantica<\/i>\n                    and\n                    <i>Oudneya africana<\/i>\n                    : Antioxidant, Anti\u2010Inflammatory, Antimicrobial, and Photoprotective Potential"],"prefix":"10.1002","volume":"22","author":[{"given":"Hajer","family":"Tlili","sequence":"first","affiliation":[{"name":"Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms Institute of Arid Regions (IRA)  Medenine Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Neji","sequence":"additional","affiliation":[{"name":"Higher School of Health Sciences and Techniques of Tunis  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelkarim Ben","family":"Arfa","sequence":"additional","affiliation":[{"name":"Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms Institute of Arid Regions (IRA)  Medenine Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3493-6451","authenticated-orcid":false,"given":"Walid","family":"Elfalleh","sequence":"additional","affiliation":[{"name":"Department of Biology College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU)  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaima","family":"Benine","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology. Faculty of Sciences of Nature and Life &amp; Laboratory of Biology Environment, and Health (LBEH), University of El Oued  El Oued Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Neffati","sequence":"additional","affiliation":[{"name":"Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms Institute of Arid Regions (IRA)  Medenine Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanen","family":"Najjaa","sequence":"additional","affiliation":[{"name":"Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms Institute of Arid Regions (IRA)  Medenine Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Cultivation of Aromatic and Medicinal 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