{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:57:25Z","timestamp":1785488245179,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Three previously undescribed compounds, 2\u03b1,3\u03b2,20\u03b1,23\u2010tetrahydroxy\u2010nor\u201030\u2010urs\u201012\u2010en\u201028\u2010oic acid 28\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010\u03b2\u2010\n                    <jats:sc>d<\/jats:sc>\n                    \u2010glucopyranoside (\n                    <jats:bold>1<\/jats:bold>\n                    ), 2\u03b1,3\u03b2,6\u03b2,23\u2010tetrahydroxyoleana\u201011,13(18)\u2010dien\u201028\u2010oic acid (\n                    <jats:bold>2<\/jats:bold>\n                    ), and 4,6\u2010dihydroxy\u20103\u2010methyl\u20102\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010\u03b2\u2010\n                    <jats:sc>d<\/jats:sc>\n                    \u2010glucopyranosylbenzophenone (\n                    <jats:bold>3<\/jats:bold>\n                    ), together with 11 known compounds (\n                    <jats:bold>4<\/jats:bold>\n                    \u2013\n                    <jats:bold>14<\/jats:bold>\n                    ) are isolated from the leaves of\n                    <jats:italic>Syzygium antisepticum<\/jats:italic>\n                    . The isolated compounds are characterized via HR\u2013ESI\u2013MS and NMR spectra. Compounds\n                    <jats:bold>1<\/jats:bold>\n                    ,\n                    <jats:bold>2<\/jats:bold>\n                    ,\n                    <jats:bold>6<\/jats:bold>\n                    , and\n                    <jats:bold>7<\/jats:bold>\n                    exhibited significant inhibition of NO production in lipopolysaccharide (LPS)\u2010activated murine macrophage RAW264.7 cells with IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 16.3, 14.9, 25.5, and 24.7\u00a0\u00b5M, respectively. In addition, compounds\n                    <jats:bold>9<\/jats:bold>\n                    \u2013\n                    <jats:bold>12<\/jats:bold>\n                    displayed the most potential \u03b1\u2010glucosidase with IC\n                    <jats:sub>50<\/jats:sub>\n                    values ranging from 23.6 to 162.0\u00a0\u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501820","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:01:26Z","timestamp":1761156086000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three Previously Undescribed Compounds Isolated From the Leaves of\n                    <i>Syzygium antisepticum<\/i>\n                    With Their \u03b1\u2010Glucosidase and Nitric Oxide Inhibitory Activity"],"prefix":"10.1002","volume":"23","author":[{"given":"Do Thi","family":"Trang","sequence":"first","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Viet","family":"Dung","sequence":"additional","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngo Anh","family":"Bang","sequence":"additional","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vu Kim","family":"Thu","sequence":"additional","affiliation":[{"name":"Faculty of Basic Sciences Hanoi University of Mining and Geology  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Thi Thuy","family":"Hang","sequence":"additional","affiliation":[{"name":"Faculty of Basic Sciences Hanoi University of Natural Resources and Environment  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pham Hai","family":"Yen","sequence":"additional","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bui Huu","family":"Tai","sequence":"additional","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0756-6990","authenticated-orcid":false,"given":"Phan","family":"Van Kiem","sequence":"additional","affiliation":[{"name":"Institute of Chemistry  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,22]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"https:\/\/www.worldfloraonline.org\/search?query=Syzygium+antisepticum."},{"key":"e_1_2_9_3_1","first-page":"51","volume-title":"An Illustrated Flora of Vietnam \u2010 Part 1","author":"Ho P. 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