{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:53:10Z","timestamp":1791409990158,"version":"4.3.3"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Lagerstroemia speciosa<\/jats:italic>\n                    is widely utilized for various ailments, including anticancer, cardiovascular, nephroprotective, hypertension, anti\u2010diabetic, etc. Phytochemical analysis of the different solvents and the SFE extracts was performed using GC\u2010MS, and the comparative antioxidant potential, along with the green\u2010synthesized gold nanoparticles, was investigated. GC\u2010MS analysis revealed the presence of major bioactive compounds, viz. mequinol, catechol, 4\u2010hydroxy\u20103\u2010methylacetophenone, ethane\u2010dioic acid, aspidospermidin\u201017\u2010ol, D\u2010limonene, and dodecanoic acid, that contribute to the antioxidant potential of the plant. Green\u2010synthesized Au\u2010NPs exhibit an absorption peak at 530\u00a0nm, demonstrate good stability, and have a surface charge of \u221232.5\u00a0mV, as characterized by zeta potential. They were crystalline in nature, spherical in shape, and had a size range of 1\u2013100\u00a0nm. Antioxidant evaluation using the DPPH method demonstrated the radical quenching activity of 71.01%\u00a0\u00b1\u00a03.12% at 40 \u00b5g\/ml in the methanol extract and 64.43%\u00a0\u00b1\u00a02.1% in the SFE, while in the ABTS assay, scavenging activity of 95.27%\u00a0\u00b1\u00a00.62% at 40 \u00b5g\/ml was reported in the aqueous extract, 79.10%\u00a0\u00b1\u00a02.9% in methanol and 50.41%\u00a0\u00b1\u00a01.52% in AuNPs as compared to the standard compound, ascorbic acid. The high scavenging potential is likely due to the high concentration of phenolic and flavonoid compounds reported through GC\u2010MS analysis. Further studies are needed to isolate the bioactive compounds.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501848","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:17:22Z","timestamp":1772965042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["GC\u2010MS\u2010Based Phytochemical Profiling and Anti\u2010Oxidant Potential of\n                    <i>Lagerstroemia Speciosa<\/i>\n                    Leaf Extracts and Their Synthesized Gold Nanoparticles"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7436-1886","authenticated-orcid":false,"given":"Tarsem","family":"Nain","sequence":"first","affiliation":[{"name":"Department of Genetics Maharshi Dayanand University  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2537-9932","authenticated-orcid":false,"given":"Navpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"National Agri\u2010Food Biotechnology Institute (NABI)  Mohali Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kajal","family":"Nagre","sequence":"additional","affiliation":[{"name":"Division of Genetics ICAR\u2010Indian Agricultural Research Institute  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh Kumar","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Genetics Maharshi Dayanand University  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3500-6811","authenticated-orcid":false,"given":"Jaya Parkash","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Genetics Maharshi Dayanand University  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/2215083806999201211213931"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9120871"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2015.04.040"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2003.11.046"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2025.107317"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rechem.2024.101559"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25074057"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbp.2010.03.002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/appliedchem2020005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijfs.16346"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matlet.2020.128344"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtice.2021.07.019"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0217979225501292"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2024.138827"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2011.09.029"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10876\u2010019\u201001508\u20109"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1049\/iet\u2010nbt.2017.0203"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010food\u2010041715\u2010033206"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2025.2479040"},{"key":"e_1_2_9_21_1","first-page":"258","article-title":"Evaluation of Antioxidant Potential and Phytochemical Characterization Using GC\u2010MS Analysis of Bioactive Compounds of Achillea filipendulina (L.) Leaves'","volume":"8","author":"Khan S.","year":"2019","journal-title":"Journal of Pharmacognosy and Phytochemistry"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.9734\/ajacr\/2020\/v6i330162"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/21691401.2025.2583019"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27051692"},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","unstructured":"B. G.Bag S. S.Dash andA.Mandal \u201cStudy of Antioxidant Property of the Rhizome Extract ofPolygonatum cirrhifolium(Mahameda) and its use in the green synthesis of Gold nanoparticles \u201d (2017).","DOI":"10.53023\/p.rasayan-20161008"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27206885"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.15835\/nsb14111098"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10070798"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.4103\/2221\u20101691.333209"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.22270\/jddt.v15i1.6973"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.5530\/ijper.55.1.25"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9080688"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.12010"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23137426"},{"key":"e_1_2_9_35_1","first-page":"208","volume-title":"Herbs and Natural Products for Neurodegenerative Disorders', Molecular Targets and Therapeutic Interventions Against Neurodegenerative Diseases","author":"Pal R. S.","year":"2025"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42535\u2010025\u201001179\u20100"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2015.03.016"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e17124"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.61.1772"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2011.07.076"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1590\/1980\u20105373\u2010mr\u20102015\u20100694"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202501848","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202501848","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202501848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T12:02:57Z","timestamp":1775995377000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202501848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/cbdv.202501848"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202501848","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-05-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01848"}}