{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:01:48Z","timestamp":1785484908675,"version":"3.56.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82374140"],"award-info":[{"award-number":["82374140"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    As a traditional Chinese medicine,\n                    <jats:italic>Centella asiatica<\/jats:italic>\n                    (CA) contains diverse chemical constituents, which serve as the basis for its broad\u2010spectrum pharmacological activities. This study aimed to investigate the therapeutic effects of CA on glycolipid metabolism disorders in ob\/ob mice and conduct a systematic qualitative and quantitative analysis of the chemical composition of CA. The results demonstrated that CA extract effectively ameliorated glucose intolerance and insulin resistance, decreased blood lipid levels, and alleviated hepatic steatosis in ob\/ob mice. A total of 39 chemical constituents were identified in the CA extract. To facilitate the quality evaluation of CA, we established a rapid and precise method for the simultaneous quantification of eight target compounds\u2014asiaticoside, asiaticoside B, madecassoside, asiatic acid, madecassic acid, stachyose, kaempferol glucuronide, and quercetin\u20103\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010glucuronide in CA medicinal materials. Notably, this study represents the first quantitative analysis of stachyose, kaempferol glucuronide, and quercetin\u20103\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010glucuronide in CA, thereby complementing and expanding the existing framework for its quality control.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202501872","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T12:03:49Z","timestamp":1767873829000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of the Chemical Composition and Glycolipid Metabolism\u2010Regulating Properties of\n                    <i>Centella asiatica<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Xin","family":"Jin","sequence":"first","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zang","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyuan","family":"Dai","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3522-0471","authenticated-orcid":false,"given":"Xinchi","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Qiu","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11101-017-9528-y"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0944-7113(00)80065-3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116746"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-14-32"},{"key":"e_1_2_9_6_1","article-title":"Screening of the Dichloromethane: Methanolic Extract of Centella asiatica for Antibacterial Activities Against Salmonella Typhi, Escherichia coli, Shigella Sonnei, Bacillus Subtilis, and Staphylococcus aureus","volume":"2020","author":"Sieberi B. 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