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There are numerous reviews on the synthesis of amide compounds; however, there are relatively few comprehensive reviews on the chemical components of amides derived from natural sources. Literature research shows that amide compounds are mainly found in traditional Chinese medicines, such as\n                    <jats:italic>Cortex Lycii<\/jats:italic>\n                    ,\n                    <jats:italic>Fructus Lycii<\/jats:italic>\n                    ,\n                    <jats:italic>Fructus Piperis Longi<\/jats:italic>\n                    , and\n                    <jats:italic>Fructus Piperis<\/jats:italic>\n                    . According to their core structural characteristics, they can be classified into phenylalkyl amides, piperidine amides, fatty amides, pyrrolidine amides, aristolactam amides, and other amides. The pharmacological effects of amide compounds mainly include anti\u2010inflammatory, hypoglycemic, antioxidant, anti\u2010cancer, anti\u2010protozoal, antiviral, and antibacterial activities. This article provides a review of the current research status of natural sources of amide chemical components and their pharmacological effects, with the aim of offering a reference for in\u2010depth exploitation and utilization of natural amide compounds.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202502202","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T11:17:02Z","timestamp":1767871022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Research Progress on Chemical Constituents and Pharmacological Effects of Amides From Natural Sources"],"prefix":"10.1002","volume":"23","author":[{"given":"Xiao\u2010fei","family":"Yang","sequence":"first","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010yuan","family":"Su","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi\u2010Xuan","family":"Long","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010qing","family":"You","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010yi","family":"Wu","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan\u2010hang","family":"Meng","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010hong","family":"Luo","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin\u2010yue","family":"Yu","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"},{"name":"The Key Research Laboratory of \u201cExploring Effective Substance in Classic and Famous Prescriptions of Traditional Chinese Medicine\u201d The State Administration of Traditional Chinese Medicine of the People's Republic of China  Beijing China"},{"name":"National Administration of Traditional Chinese Medicine High Level Key Discipline Construction Project of Traditional Chinese Medicine Chemistry of Chinese Material Medica  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5057-7794","authenticated-orcid":false,"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"},{"name":"The Key Research Laboratory of \u201cExploring Effective Substance in Classic and Famous Prescriptions of Traditional Chinese Medicine\u201d The State Administration of Traditional Chinese Medicine of the People's Republic of China  Beijing China"},{"name":"National Administration of Traditional Chinese Medicine High Level Key Discipline Construction Project of Traditional Chinese Medicine Chemistry of Chinese Material Medica  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"issue":"08","key":"e_1_2_8_2_1","first-page":"08","article-title":"Research Progress on Chemical Constituents of Lycii Cortex","volume":"48","author":"Lu L. 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