{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T13:04:19Z","timestamp":1776344659269,"version":"3.51.2"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:00:00Z","timestamp":1758585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:00:00Z","timestamp":1758585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Mimosa tenuiflora<\/jats:italic>\n                    (Willd.) Poir., known as \u201cJurema\u2010preta\u201d, is a species of ethnobotanical relevance, used in traditional medicine. The northeastern backland is characterized by climatic variability, which makes it essential to carry out studies that assess the seasonal influence on the chemical profile of native species. The aim of this study was to evaluate the seasonal variation in the chemical constituents of\n                    <jats:italic>M. tenuiflora<\/jats:italic>\n                    over a 24\u2010month period. Plant collections were made bimonthly in the municipality of Petrolina, Pernambuco, Brazil. The plant material was dried, pulverized, and extracted with ethanol (1:10, w\/v) for 72 h under magnetic stirring. The analyses included the quantification of secondary metabolites, the development of a method using high\u2010performance liquid chromatography with a diode array detector for the quantification of\n                    <jats:italic>N,N<\/jats:italic>\n                    \u2010dimethyltryptamine (DMT), and multivariate statistical analysis using principal component analysis. The results indicated that phenolic compounds, especially flavonoids, are associated with water stress, radiation, and temperature. DMT production showed a negative correlation with radiation and temperature, but not with precipitation. Total alkaloids and yield showed little correlation with climatic variables. This study reinforces the importance of seasonality in the planning of plant collection and the pharmacological use of\n                    <jats:italic>M. tenuiflora<\/jats:italic>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>M. tenuiflora<\/jats:italic>\n                    , \u201cJurema preta\u201d, seasonality, HPLC\u2010DAD, PCA\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202502234","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T15:57:58Z","timestamp":1758643078000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seasonal Effect on the Chemical Composition of\n                    <i>Mimosa tenuiflora<\/i>\n                    (Willd.) Poir Stem Bark from the Semi\u2010Arid Region of Pernambuco, Brazil"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1126-0126","authenticated-orcid":false,"given":"Nath\u00e1lia Andrezza Carvalho","family":"de Souza","sequence":"first","affiliation":[{"name":"Northeast Network of Biotechnology (RENORBIO) Federal Rural University of Pernambuco (UFRPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2644-6943","authenticated-orcid":false,"given":"Pedro Guilherme Sousa de","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"Northeast Network of Biotechnology (RENORBIO) Federal Rural University of Pernambuco (UFRPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4376-9912","authenticated-orcid":false,"given":"Tarc\u00edsio C\u00edcero de Lima","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Northeast Network of Biotechnology (RENORBIO) Federal Rural University of Pernambuco (UFRPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5906-8227","authenticated-orcid":false,"given":"Vict\u00f3ria Laysna dos Anjos","family":"Santos","sequence":"additional","affiliation":[{"name":"Northeast Network of Biotechnology (RENORBIO) Federal Rural University of Pernambuco (UFRPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3260-2220","authenticated-orcid":false,"given":"Guilherme Urias Menezes","family":"Novaes","sequence":"additional","affiliation":[{"name":"Northeast Network of Biotechnology (RENORBIO) Federal Rural University of Pernambuco (UFRPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1867-9096","authenticated-orcid":false,"given":"Emerson de Oliveira","family":"Silva","sequence":"additional","affiliation":[{"name":"Federal University of Pernambuco (UFPE)  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0753-6601","authenticated-orcid":false,"given":"Heberte Fernandes de","family":"Figueredo","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Agronomy Federal University of Vale do S\u00e3o Francisco (UNIVASF)  Petrolina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9458-1744","authenticated-orcid":false,"given":"Raimundo Gon\u00e7alves de","family":"Oliveira\u2010J\u00fanior","sequence":"additional","affiliation":[{"name":"UMR CNRS 8038 CiTCoM Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1657-2997","authenticated-orcid":false,"given":"Rapha\u00ebl","family":"Grougnet","sequence":"additional","affiliation":[{"name":"UMR CNRS 8038 CiTCoM Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2403-1026","authenticated-orcid":false,"given":"Larissa Ara\u00fajo","family":"Rolim","sequence":"additional","affiliation":[{"name":"Federal University of Vale do S\u00e3o Francisco (UNIVASF)  Petrolina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/0100\u201085872018v38n1cap05"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10508619.2023.2185369"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2024.108076"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.flora.2022.152121"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43450\u2010022\u201000322\u20101"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2021.03.010"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2024.2405875"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11101\u2010024\u201009919\u2010x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/1983\u201021252020v33n116rc"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2018.03.017"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e24068"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2020.126277"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.21577\/0103\u20105053.20230147"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.21577\/0103\u20105053.20220117"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2015.0202"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/1980\u2010549720190041"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327906mbr0102_10"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2020.02.002"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhydrol.2024.130850"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/0102\u201077863630138"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stress.2023.100241"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/d0fo02324h"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X211069721"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2023.1140509"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmpp.2024.102383"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s44372\u2010024\u201000063\u20106"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010023\u201005435\u20104"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2014.12.005"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.34172\/apb.2022.010"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stress.2023.100154"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.102"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2020.1844086"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2021.111932"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906\u2010018\u20102114\u2010z"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436\u2010015\u20104747\u2010x"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202502234","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202502234","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202502234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T11:51:13Z","timestamp":1773489073000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202502234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,23]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/cbdv.202502234"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202502234","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,23]]},"assertion":[{"value":"2025-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02234"}}