{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:01:49Z","timestamp":1785484909063,"version":"3.56.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104524"],"award-info":[{"award-number":["82104524"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Linderasesterterpenoids C\u2212H (\n                    <jats:bold>1<\/jats:bold>\n                    \u2212\n                    <jats:bold>6<\/jats:bold>\n                    ), six novel sesterterpenoids featuring an unprecedented 7\u2010cyclohexyldecahydroazulene carbon skeleton, were isolated from the root of\n                    <jats:italic>Lindera glauca<\/jats:italic>\n                    (\n                    <jats:italic>L. glauca<\/jats:italic>\n                    ). Their structures were elucidated by quantum chemical calculations and spectroscopic methods. In the bioassay, linderasesterterpenoid C (\n                    <jats:bold>1<\/jats:bold>\n                    ) exhibited inhibitory activity against lipopolysaccharide\u2010induced nitric oxide (NO) production in RAW 264.7 cells compared to a positive control. Western blot analysis further indicated that compound\n                    <jats:bold>1<\/jats:bold>\n                    decreased the level of pro\u2010inflammatory enzymes, inducible NO synthase.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503028","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T20:36:21Z","timestamp":1761424581000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Six Novel Sesterterpenoids Isolated From the Root of\n                    <i>Lindera glauca<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Jingxin","family":"He","sequence":"first","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingnan","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuxing","family":"Liang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingming","family":"Luo","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqin","family":"Wei","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiting","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zelin","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4281-016X","authenticated-orcid":false,"given":"Hui","family":"Cui","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"},{"name":"Key Laboratory of Tropical Medicinal Resource Chemistry of the Ministry of Education Hainan Normal University  Haikou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqian","family":"Tang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chinese Medicinal Resource from Lingnan Ministry of Education School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107686"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4NP00041B"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2010.06.002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272\u2010016\u20100838\u20101"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.104871"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC09159A"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000536491"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.2c01364"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1875\u20105364(24)60657\u20106"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b04648"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/np500077z"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202503028","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202503028","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202503028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T07:57:12Z","timestamp":1785484632000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202503028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,25]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/cbdv.202503028"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202503028","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,25]]},"assertion":[{"value":"2025-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03028"}}