{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:02:22Z","timestamp":1775890942224,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019YFC1712304"],"award-info":[{"award-number":["2019YFC1712304"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","award":["GXZYZ20210068"],"award-info":[{"award-number":["GXZYZ20210068"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011833","name":"Guangxi University of Chinese Medicine","doi-asserted-by":"publisher","award":["2020ZD002,YCXJ2021020"],"award-info":[{"award-number":["2020ZD002,YCXJ2021020"]}],"id":[{"id":"10.13039\/501100011833","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Four new triterpenoids, pirifoliusic acids B\u2013E, together with seven known compounds (\n                    <jats:bold>5<\/jats:bold>\n                    \u2013\n                    <jats:bold>11<\/jats:bold>\n                    ), have been isolated from\n                    <jats:italic>Rubus pirifolius<\/jats:italic>\n                    Smith. All these structures were determined by spectroscopic techniques. All the isolated triterpenoids were assessed for cytotoxicity against HL\u201060 (leukemia), A549 (lung), SMMC\u20107721 (liver), MDA\u2010MB\u2010231 (breast), and SW480 (colon) cancer cell lines. Among them, compounds\n                    <jats:bold>10<\/jats:bold>\n                    and\n                    <jats:bold>11<\/jats:bold>\n                    exhibited significant cytotoxicities against these five cancer cell lines.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503037","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T20:46:39Z","timestamp":1769892399000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Four New Triterpenoids From\n                    <i>Rubus pirifolius<\/i>\n                    Smith"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1848-7928","authenticated-orcid":false,"given":"Xiao\u2010Yan","family":"Ning","sequence":"first","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei\u2010Fang","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Jiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Feng","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen\u2010Yan","family":"Liang","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"Guangxi Engineering and Technology Research Center for the Development of Proprietary Chinese Medicine and Ethnic Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng\u2010Sheng","family":"Lu","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"Guangxi Engineering and Technology Research Center for the Development of Proprietary Chinese Medicine and Ethnic Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liu\u2010Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"Guangxi Engineering and Technology Research Center for the Development of Proprietary Chinese Medicine and Ethnic Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0075-2248","authenticated-orcid":false,"given":"Jian\u2010Hua","family":"Wei","sequence":"additional","affiliation":[{"name":"Guangxi University of Chinese Medicine  Nanning P. R. China"},{"name":"National Demonstration Center for Experimental Chinese Medicine Education Guangxi University of Chinese Medicine  Nanning P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Practical Yao Pharmacy","author":"Pang S.\u2010H.","year":"2008"},{"key":"e_1_2_9_3_1","volume-title":"Chemical and Pharmacological Studies on Common Plant Medicines in Yao Medicine","author":"Yi X.\u2010H.","year":"2008"},{"key":"e_1_2_9_4_1","volume-title":"List of Traditional Chinese Medicine Resources in Guangxi","author":"Fang D.","year":"1993"},{"key":"e_1_2_9_5_1","first-page":"36","article-title":"Classification and Source of 164 Characteristic Zhuang Medicine","volume":"17","author":"Lan R.\u2010C.","year":"2011","journal-title":"J Med & Pharm Chin Minor"},{"key":"e_1_2_9_6_1","first-page":"24","article-title":"Chemical Composition of Rubus pirifolius Smith","volume":"10","author":"Wang L.\u2010P.","year":"2019","journal-title":"Medicinal Plants"},{"key":"e_1_2_9_7_1","first-page":"3065","article-title":"Two New 2,3\u2010seco Triterpenoids From Rubus pirifolius Smith","volume":"58","author":"Ning X.\u2010Y.","year":"2023","journal-title":"Acta Pharmaceutica Sinica"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bse.2023.104686"},{"key":"e_1_2_9_9_1","first-page":"1","article-title":"Noroleanane\u2010type Triterpenoids From Dolichos trilobus L. and Their Anti\u2010a\u2010glucosidase Activities","volume":"31","author":"Luo M.","year":"2019","journal-title":"Natural Product Research"},{"key":"e_1_2_9_10_1","first-page":"451","article-title":"Chemical Constituents From Medical and Edible Plants of Rosa roxburghii","volume":"41","author":"Li Q.\u2010J.","year":"2016","journal-title":"China Journal of Chinese Materia Medica"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2008.12.052"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2017.11.005"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(88)83061-9"},{"key":"e_1_2_9_14_1","first-page":"3897","article-title":"Chemical Constituents From Rubi fructus","volume":"53","author":"Wang J.\u2010Y.","year":"2022","journal-title":"Chinese Traditional and Herbal Drugs"},{"key":"e_1_2_9_15_1","first-page":"5740","article-title":"A New Seco\u2010triterpene From Roots of Rosa laevifgata","volume":"49","author":"Liu Y.\u2010H.","year":"2018","journal-title":"Chinese Traditional and Herbal Drugs"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2005.05.072"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.c15-00831"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-019-02699-3"},{"key":"e_1_2_9_19_1","first-page":"162","article-title":"A Pair of New Isoflavonoid Enantiomers From Dalbergia benthamii Prain","volume":"58","author":"Ning X.\u2010Y.","year":"2023","journal-title":"Acta Pharmaceutica Sinica"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202503037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202503037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202503037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:35:11Z","timestamp":1775889311000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202503037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/cbdv.202503037"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202503037","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,31]]},"assertion":[{"value":"2025-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03037"}}