{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:01:48Z","timestamp":1785484908264,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Three rare pyrazine\u2010containing alkaloid heterodimers scosubspiloids A\u2013C (\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>3<\/jats:bold>\n                    ) and one new spiro\u2010indole heterodimer scosubspiloid D (\n                    <jats:bold>4<\/jats:bold>\n                    ), along with seven known alkaloids (\n                    <jats:bold>5<\/jats:bold>\n                    \u2013\n                    <jats:bold>11<\/jats:bold>\n                    ) were isolated from\n                    <jats:italic>Scolopendra subspinipes mutilans<\/jats:italic>\n                    . Spectroscopic methods and ECD calculations were used to identify their structures. Biologically,\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>3<\/jats:bold>\n                    could significantly inhibit the proliferation of MDA\u2010MB\u2010231 cells at 20\u00a0\u00b5M. The investigation provided experimental evidences to support the traditional use of\n                    <jats:italic>S. subspinipes mutilans<\/jats:italic>\n                    in treating cancer, and revealed new structure type compounds in the medicinal animal.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503282","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T18:45:43Z","timestamp":1765392343000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Four New Alkaloid Heterodimers From\n                    <i>Scolopendra subspinipes mutilans<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Bin\u2010Yuan","family":"Hu","sequence":"first","affiliation":[{"name":"School of Chinese Materia Medica &amp;Yunnan Key Laboratory of Southern Medicine Utilization Yunnan International Joint Laboratory for Exploration and Utilization of Aromatic Chinese Medicinal Materials in Agriculture, Yunnan University of Chinese Medicine  Kunming People's Republic of China"},{"name":"Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics Institute for Inheritance\u2010Based Innovation of Chinese Medicine School of Pharmacy Shenzhen University Medical School Shenzhen University  Shenzhen People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Fu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics Institute for Inheritance\u2010Based Innovation of Chinese Medicine School of Pharmacy Shenzhen University Medical School Shenzhen University  Shenzhen People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu\u2010Mei","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica &amp;Yunnan Key Laboratory of Southern Medicine Utilization Yunnan International Joint Laboratory for Exploration and Utilization of Aromatic Chinese Medicinal Materials in Agriculture, Yunnan University of Chinese Medicine  Kunming People's Republic of China"},{"name":"Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics Institute for Inheritance\u2010Based Innovation of Chinese Medicine School of Pharmacy Shenzhen University Medical School Shenzhen University  Shenzhen People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1643-9598","authenticated-orcid":false,"given":"Yong\u2010Xian","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica &amp;Yunnan Key Laboratory of Southern Medicine Utilization Yunnan International Joint Laboratory for Exploration and Utilization of Aromatic Chinese Medicinal Materials in Agriculture, Yunnan University of Chinese Medicine  Kunming People's 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