{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:45:52Z","timestamp":1791081952221,"version":"4.1.0"},"reference-count":59,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Panax ginseng<\/jats:italic>\n                    is a well\u2010known medicinal and edible plant rich in polysaccharides. However, research on the impact of microwave power (MP) on ginseng polysaccharides (GPs) remains limited. This study investigated the effects of varying MP (300\u2013700\u00a0W) on the structure and bioactivity of microwave\u2010extracted polysaccharide (MEP) using spectroscopy, and chromatography, and by evaluating antioxidant, antitumor, and immunomodulatory activities. The results were determined under the extraction conditions of 300 and 700\u00a0W that showed the polysaccharide yield (40.15%\u00a0vs. 47.97%), content (85.77%\u00a0vs. 88.60%), and the IC\n                    <jats:sub>50<\/jats:sub>\n                    values for \u00b7OH scavenging ability (7.67\u00a0\u00b1\u00a00.25\u00a0mg\/mL vs. 8.53\u00a0\u00b1\u00a00.18\u00a0mg\/mL). The inhibition rates against HeLa cells at a polysaccharide concentration of 10\u00a0mg\/mL were 26.78% and 1.08%, respectively. The release of nitric oxide (NO) at a polysaccharide concentration of 250 \u00b5g\/mL was 2.23 and 1.82 \u00b5mol\/L, respectively. Notably, the polysaccharides obtained at 700\u00a0W exhibited weak bioactivity, primarily due to severely damaged structure characterized by extensive\n                    <jats:italic>O<\/jats:italic>\n                    \u2010glycosidic bond cleavage, a significant reduction in molecular weight, and the worst thermal stability. Overall, these findings emphasize how MP affects polysaccharide structure and function, offering critical insights for processing other plant\u2010derived polysaccharides.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503344","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T07:08:59Z","timestamp":1773904139000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of Microwave Extraction Power on Physicochemical Properties, Structure, and Biological Activity of Polysaccharides From Ginseng"],"prefix":"10.1002","volume":"23","author":[{"given":"Tianyue","family":"Liu","sequence":"first","affiliation":[{"name":"School of Chemistry and Pharmaceutical Engineering Jilin University of Chemical Technology  Jilin P. R. 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