{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:15Z","timestamp":1788858555254,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T00:00:00Z","timestamp":1786147200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Alternaria alternata<\/jats:italic>\n                    infects grapes postharvest and causes harmful fruit rot. This study evaluated\n                    <jats:italic>Tetraclinis articulata<\/jats:italic>\n                    essential oil (TA\u2010EO) nanoemulsion as a sustainable biocontrol strategy for\n                    <jats:italic>Vitis vinifera<\/jats:italic>\n                    cv. Red Globe. After storage, grapes were inoculated with\n                    <jats:italic>A. alternata<\/jats:italic>\n                    and treated with TA\u2010EO nanoemulsions at different concentrations. Disease severity index (DSI), total polyphenol, flavonoid contents, and antioxidant activity were evaluated after 3, 6, 9, and 12 days. The EO, rich in \u03b1\u2010pinene, camphor, and limonene, was successfully encapsulated into a stable nanoemulsion (358\u2013392\u00a0nm; \u221240\u00a0mV). In vitro, nanoemulsion showed a minimum inhibitory concentration (MIC) of 500\u00a0\u00b5g\/mL and a selectivity index (SI) of 1. In vivo, treatment at 2\u00a0g\/L reduced DSI to 9.9% after 12 days versus 69.5% in the untreated control, comparable to a commercial fungicide (10.2%). Treated grapes maintained higher polyphenol (20.20\u00a0mg GAE\/g DW) and flavonoid contents (48.83\u00a0mg QE\/g DW), with stronger antioxidant activity (IC\n                    <jats:sub>50<\/jats:sub>\n                    = 284.73\u00a0\u00b5g\/mL; molecular docking, revealing strong interactions of \u03b1\u2010terpineol and terpinen\u20104\u2010ol with\n                    <jats:italic>A. alternata<\/jats:italic>\n                    thioredoxin reductase and membrane transporters. This method extended 12 days shelf\u2010life grapes by comparison to the control group. This approach represents an eco\u2010safe strategy EC\n                    <jats:sub>50<\/jats:sub>\n                    = 182.10\u00a0\u00b5g\/mL) than infected controls for sustainable viticulture.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503424","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T17:31:49Z","timestamp":1786210309000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Postharvest Control of\n                    <i>Alternaria alternata<\/i>\n                    in Table Grapes Using a\n                    <i>Tetraclinis articulata<\/i>\n                    Essential Oil Nanoemulsion: Antifungal Activity and Molecular Docking Insights"],"prefix":"10.1002","volume":"23","author":[{"given":"Safa","family":"Rguez","sequence":"first","affiliation":[{"name":"Laboratory of Aromatic and Medicinal Plants Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rym","family":"Essid","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Parasitology Biotechnology and Biomolecules Institut Pasteur of Tunisia  Belvedere Tunisia"},{"name":"Laboratory of Bioactive Substances Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majdi","family":"Hammami","sequence":"additional","affiliation":[{"name":"Laboratory of Aromatic and Medicinal Plants Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naceur","family":"Dj\u00e9bali","sequence":"additional","affiliation":[{"name":"Laboratory of Bioactive Substances Center of Biotechnology of Borj Cedria  Hammam\u2010Lif 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Aromatic and Medicinal Plants Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olfa","family":"Frouja","sequence":"additional","affiliation":[{"name":"Laboratory of Aromatic and Medicinal Plants Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olfa","family":"Tabbene","sequence":"additional","affiliation":[{"name":"Laboratory of Bioactive Substances Center of Biotechnology of Borj Cedria  Hammam\u2010Lif Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibtissem Hamrouni","family":"Sellami","sequence":"additional","affiliation":[{"name":"Laboratory of Aromatic and Medicinal Plants Center of Biotechnology of Borj Cedria  Hammam\u2010Lif 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