{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T12:46:18Z","timestamp":1775997978512,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009007","name":"Guangxi Normal University","doi-asserted-by":"publisher","award":["CMEMR2023\u2010B13"],"award-info":[{"award-number":["CMEMR2023\u2010B13"]}],"id":[{"id":"10.13039\/501100009007","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A deep eutectic solvent (DES)\u2010based three\u2010phase partitioning (TPP) was developed for efficient and green extraction of\n                    <jats:italic>Bombax ceiba<\/jats:italic>\n                    flower polysaccharide (BCFP). DES\u20101 (lauric acid and decanoic acid) was chosen as the optimal solvent. The extraction yield of BCFP reached 13.53% under optimal conditions: 5% (w\/v) mass fraction of (NH\n                    <jats:sub>4<\/jats:sub>\n                    )\n                    <jats:sub>2<\/jats:sub>\n                    SO\n                    <jats:sub>4<\/jats:sub>\n                    , 25:1 (v\/w) of DES\u20101 to crude powder, Lauric acid to decanoic acid ratio of 1:1, 10\u00a0min and 40\u00b0C. The main monosaccharides of BCFP included mannose, rhamnose, glucuronic acid (GluA), galacturonic acid (GalA), glucose, xylose, galactose, and arabinose. The obtained BCFP was characterized as acidic heteropolysaccharide with an average molecular weight of 2.15\u00a0kDa, composed of galactose, arabinose, mannose, glucose, galacturonic acid (GalA), rhamnose, xylose, and glucuronic acid (GluA). In a dextran sulfate sodium (DSS)\u2010induced ulcerative colitis (UC) mouse model, BCFP administration significantly attenuated DSS\u2010induced disease activity index (DAI), body weight loss, colon shortening, spleen coefficient decreasing and histological changes. Moreover, BCFP suppressed inflammatory cytokine levels, reduced oxidative stress, and restored intestinal barrier function by enhancing mucus secretion and tight junction protein expression. This study provides an economical and environmentally friendly separation of bioactive polysaccharides from\n                    <jats:italic>B. ceiba<\/jats:italic>\n                    flower, which has potential for functional food and pharmaceutical applications in colitis management.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503434","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:41:01Z","timestamp":1773128461000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Polysaccharides From\n                    <i>Bombax ceiba<\/i>\n                    Flower by Deep Eutectic Solvent Based Three\u2010Phase Partitioning and Their Protective Effects Against DSS\u2010Induced Colitis in Mice"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6998-0025","authenticated-orcid":false,"given":"Qian","family":"Zhang","sequence":"first","affiliation":[{"name":"Dongguan Qingxi Hospital  Dongguan P. R. China"},{"name":"School of Pharmacy Guangdong Pharmaceutical University  Guangzhou P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaoting","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Pharmacy Guangdong Pharmaceutical University  Guangzhou P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyang","family":"Gu","sequence":"additional","affiliation":[{"name":"School of Pharmacy Guangdong Pharmaceutical University  Guangzhou P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Li","sequence":"additional","affiliation":[{"name":"Dongguan Qingxi Hospital  Dongguan P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences  Guangzhou P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binming","family":"Ye","sequence":"additional","affiliation":[{"name":"Dongguan Qingxi Hospital  Dongguan P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Dongguan Qingxi Hospital  Dongguan P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, School of Pharmacy, The Affiliated Dongguan Songshan Lake Central Hospital Guangdong Medical University  Dongguan P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guohua","family":"Liu","sequence":"additional","affiliation":[{"name":"Dongguan Qingxi Hospital  Dongguan P. R. 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