{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:14:12Z","timestamp":1783368852673,"version":"3.54.6"},"reference-count":55,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T00:00:00Z","timestamp":1780185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T00:00:00Z","timestamp":1780185600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In rural regions, various plant species are still utilized based on empirical knowledge passed down through generations without formal scientific validation.\n                    <jats:italic>Capparis multiflora<\/jats:italic>\n                    Hook.f. &amp; Thomson is one such plant traditionally used in Arunachal Pradesh, India, where the stem is employed as an ethnomedicinal remedy for the treatment of boils and navel infections. The present study aims to scientifically validate the traditional use of\n                    <jats:italic>C. multiflora<\/jats:italic>\n                    stem and leaves. Our study investigates the antimicrobial, anti\u2010inflammatory, and antioxidant activities of various extracts obtained from the stem and leaves of\n                    <jats:italic>C. multiflora<\/jats:italic>\n                    , alongside phytochemical profiling using high\u2010performance liquid chromatography coupled with tandem mass spectrometry (HPLC\u2013MS\/MS) analytical techniques. The extracts demonstrated significant antimicrobial, anti\u2010inflammatory, and antioxidant activities. Furthermore, HPLC\u2013MS\/MS analysis tentatively identified previously reported bioactive antimicrobial and anti\u2010inflammatory compounds. These findings collectively provide scientific evidence supporting the traditional use of\n                    <jats:italic>C. multiflora<\/jats:italic>\n                    stem in the management of boils and navel infections. Further studies including wound healing, dermal infection, biofilm inhibition, and in vivo models are required to confirm these effects.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503529","type":"journal-article","created":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T18:21:06Z","timestamp":1780251666000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unlocking the Bioactive Potential of\n                    <i>Capparis multiflora<\/i>\n                    From Northeast India: First\u2010Ever LC\u2013MS Profiling and Biological Activity Studies"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5176-221X","authenticated-orcid":false,"given":"Tage","family":"Seema","sequence":"first","affiliation":[{"name":"Department of Chemistry Rajiv Gandhi University  Doimukh Arunachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6720-2200","authenticated-orcid":false,"given":"Jyoti Lakshmi","family":"Hati Boruah","sequence":"additional","affiliation":[{"name":"Biological Sciences &amp; Technology Division CSIR\u2010North East Institute of Science &amp; Technology  Jorhat Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjib Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Biotechnology NEMCARE Group of Institutions  Guwahati Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshyajeet","family":"Nath","sequence":"additional","affiliation":[{"name":"Department of Pharmacology NEMCARE Group of Institutions  Guwahati Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lobsang","family":"Zimba","sequence":"additional","affiliation":[{"name":"Department of Chemistry Rajiv Gandhi University  Doimukh Arunachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6054-4662","authenticated-orcid":false,"given":"Dwipen","family":"Kakati","sequence":"additional","affiliation":[{"name":"Department of Chemistry Rajiv Gandhi University  Doimukh Arunachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378\u20108741(83)90052\u20101"},{"issue":"3","key":"e_1_2_11_3_1","first-page":"463","article-title":"Use of Medicinal Plants by Traditional Herbal Healers in Central India","volume":"131","author":"Rai R.","year":"2005","journal-title":"Indian 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