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Structural elucidation was performed using various techniques, including infrared spectroscopy, ultraviolet spectroscopy, high\u2010resolution electrospray ionization mass spectrometry, electronic circular dichroism spectroscopy, and nuclear magnetic resonance spectroscopy. The cardioprotective effects of the compounds were evaluated using an oxygen\u2013glucose deprivation\u2013induced injury model in H9c2 cells. At 10\u00a0\u00b5M, all compounds were nontoxic; however, compounds\n                    <jats:bold>5<\/jats:bold>\n                    and\n                    <jats:bold>12<\/jats:bold>\n                    significantly increased the cell viability, positioning them as promising lead compounds for cardioprotective drug development.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503550","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:20:25Z","timestamp":1773015625000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Four New Phenolic Glycosides From the Roots of\n                    <i>Ilex pubescens<\/i>\n                    \u00a0and Their Cardioprotective Effects"],"prefix":"10.1002","volume":"23","author":[{"given":"Zi\u2010Hao","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Shenzhen Bao'an District Traditional Chinese Medicine Hospital The Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang\u2010Qiao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute For Translational Chinese Medicine, School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010Qi","family":"Jiao","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute For Translational Chinese Medicine, School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong\u2010Qiu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Shenzhen Bao'an District Traditional Chinese Medicine Hospital The Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute For Translational Chinese Medicine, School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou China"},{"name":"Chinese Medicine Guangdong Laboratory (Hengqin Laboratory) Guangdong\u2010Macao In\u2010Depth Cooperation Zone in Hengqin  Hengqin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010Yuan","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Shenzhen Bao'an District Traditional Chinese Medicine Hospital The Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute For Translational Chinese Medicine, School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou China"},{"name":"Chinese Medicine Guangdong Laboratory (Hengqin Laboratory) Guangdong\u2010Macao In\u2010Depth Cooperation Zone in Hengqin  Hengqin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui\u2010Ling","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Shenzhen 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