{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T12:45:26Z","timestamp":1775997926871,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Two new steroid derivatives, 3\u2010oxoergosta\u20104,6,8(14),22\u2010tetraen\u201027\u2010oic acid (\n                    <jats:bold>1<\/jats:bold>\n                    ) and (14\n                    <jats:italic>R<\/jats:italic>\n                    ,24\n                    <jats:italic>R<\/jats:italic>\n                    )\u201014\u2010methyl\u201024,25\u2010dihydroxycholesta\u20104,8\u2010dien\u20103\u2010one (\n                    <jats:bold>2<\/jats:bold>\n                    ), together with one anthraquinone (\n                    <jats:bold>3<\/jats:bold>\n                    ), one amino acid derivative (\n                    <jats:bold>4<\/jats:bold>\n                    ), five cyclic dipeptides (\n                    <jats:bold>5\u20109<\/jats:bold>\n                    ) and a quinazolinone alkaloid (\n                    <jats:bold>10<\/jats:bold>\n                    ), were isolated from a deep\u2010sea\u2010derived\n                    <jats:italic>Aspergillus versicolor<\/jats:italic>\n                    SCSIO 41325. Notably, compound\n                    <jats:bold>2<\/jats:bold>\n                    features an unreported cholesta\u20104,8\u2010dien\u20103\u2010one steroid scaffold among natural products. The structures were determined by NMR and high\u2010resolution electrospray ionization mass spectroscopy (HR\u2010ESI\u2010MS) spectroscopic methods, single\u2010crystal x\u2010ray diffraction measurements and comparison with literature data. All isolated compounds were subjected to a broad range of biological assays, including tests against pathogenic bacteria and fungi, as well as for inhibition of pancreatic lipase, acetylcholinesterase, neuraminidase, and antioxidant activity evaluations.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503643","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:26:42Z","timestamp":1773030402000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two New Steroid Derivatives From the Deep\u2010Sea\u2010Derived Fungus\n                    <i>Aspergillus versicolor<\/i>\n                    SCSIO 41325"],"prefix":"10.1002","volume":"23","author":[{"given":"Shengyi","family":"Deng","sequence":"first","affiliation":[{"name":"Wuya College of Innovation Shenyang Pharmaceutical University  Shenyang China"},{"name":"Guangdong Key Laboratory of Marine Materia Medica, South China Sea 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