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The development of diabetic foot infection (DFI) is typically attributed to a combination of factors, including persistent hyperglycemia, impaired immune function, peripheral neuropathy, and vascular insufficiency. Early diagnosis and prompt treatment are crucial for favorable outcomes; however, the growing prevalence of antibiotic\u2010resistant pathogens presents a significant challenge, placing additional strain on healthcare systems. Considering these concerns, there is an increasing interest in herbal therapies with antimicrobial, anti\u2010inflammatory, and wound\u2010healing properties\u2014such as garlic (\n                    <jats:italic>Allium sativum<\/jats:italic>\n                    ), turmeric (\n                    <jats:italic>Curcuma longa<\/jats:italic>\n                    ), and neem (\n                    <jats:italic>Azadirachta indica<\/jats:italic>\n                    )\u2014as potential adjunct or alternative treatments. This review explores key aspects of DFI, including its pathophysiology, global prevalence, statistical data, risk factors, diagnostic approaches, current and potential herbal treatments, associated challenges, and future directions.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503644","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T09:36:39Z","timestamp":1773394599000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Nano\u2010Enabled Herbal Therapeutics for Diabetic Foot Ulcers: Translating Ethnopharmacological Bioactives into Advanced Wound Care"],"prefix":"10.1002","volume":"23","author":[{"given":"Manoj Kumar","family":"Mishra","sequence":"first","affiliation":[{"name":"Amity Institute of Pharmacy Amity University Madhya Pradesh  Gwalior Madhya Pradesh 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