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Traditional Anatolian folk medicine has long relied on plant\u2010based remedies to manage these conditions, offering a valuable reservoir of therapeutic knowledge. Ethnobotanical data on Anatolian medicinal plants are integrated to evaluate their therapeutic relevance through a mechanistic perspective. A meta\u2010analysis of 187 ethnobotanical studies published since 1991 was conducted, with 110 meeting strict inclusion criteria. The dataset includes 508 plant taxa, with prominent families such as Rosaceae, Lamiaceae, Asteraceae, and Malvaceae. Key species include\n                    <jats:italic>Cydonia oblonga<\/jats:italic>\n                    ,\n                    <jats:italic>Glycyrrhiza glabra<\/jats:italic>\n                    ,\n                    <jats:italic>Juniperus oxycedrus<\/jats:italic>\n                    ,\n                    <jats:italic>Matricaria chamomilla<\/jats:italic>\n                    ,\n                    <jats:italic>Pinus<\/jats:italic>\n                    spp.,\n                    <jats:italic>Plantago<\/jats:italic>\n                    spp.,\n                    <jats:italic>Rubus<\/jats:italic>\n                    spp.,\n                    <jats:italic>Sambucus nigra<\/jats:italic>\n                    , and\n                    <jats:italic>Urtica dioica<\/jats:italic>\n                    . A clear divergence in treatment strategies is evident. Essential oil\u2010 and anthocyanin\u2010rich taxa are associated with acute conditions via antimicrobial activity and \u03b3\u03b4 T\u2010cell modulation. In contrast, mucilage\u2010 and iridoid\u2010rich species are linked to chronic conditions, where mucosal protection and regulation of NF\u2010\u03baB and COX\u20102 pathways represent central mechanisms. A coherent framework for evidence\u2010based respiratory therapeutics emerges from ethnobotanical evidence integrated with mechanistic insights and updated toxicological evaluation. This review defines the mechanistic and ethnopharmacological landscape of plant\u2010based interventions targeting respiratory disorders.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503666","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T12:43:27Z","timestamp":1780145007000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties"],"prefix":"10.1002","volume":"23","author":[{"given":"Golshan","family":"Zare","sequence":"first","affiliation":[{"name":"Faculty of Pharmacy Department of Pharmaceutical Botany Hacettepe University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u011fmur","family":"Diker","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy Department of Pharmaceutical Botany Hacettepe University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irem","family":"Tatl\u0131 \u00c7ankaya","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy Department of Pharmaceutical Botany Hacettepe University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7367-1484","authenticated-orcid":false,"given":"Emran","family":"Habibi","sequence":"additional","affiliation":[{"name":"Centre For Natural Products Discovery (CNPD) School of Pharmacy and Biomolecular Sciences Liverpool John Moores University  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satyajit D.","family":"Sarker","sequence":"additional","affiliation":[{"name":"Centre For Natural Products Discovery (CNPD) School of Pharmacy and Biomolecular Sciences Liverpool John Moores University  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutfun","family":"Nahar","sequence":"additional","affiliation":[{"name":"Centre For Natural Products Discovery (CNPD) School of Pharmacy and Biomolecular Sciences Liverpool John Moores University  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001\u2010022\u201000874\u2010x"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2156587216641831"},{"key":"e_1_2_14_4_1","volume-title":"The Flora of T\u00fcrkiye and the East Aegean Islands: v. 10: and the East Aegean Islands","author":"Davis P.","year":"1988"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378\u20108741(00)00399\u20108"},{"key":"e_1_2_14_6_1","unstructured":"A.G\u00fcnerandS.Aslan \u201cT\u00fcrkiye bitkileri listesi:(damarl\u0131 bitkiler) \u201d (2012) Nezahat G\u00f6kyi\u01e7it Botanik Bah\u00e7esi Yay\u0131nlar\u0131."},{"key":"e_1_2_14_7_1","doi-asserted-by":"crossref","unstructured":"M.Co\u0219kunandA. 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