{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T16:04:13Z","timestamp":1785341053329,"version":"3.55.0"},"reference-count":56,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Andryala mogadorensis<\/jats:italic>\n                    is a rare Moroccan endemic species traditionally used for inflammatory conditions. This study evaluated the in vitro antioxidant and anti\u2010protein denaturation activities of its hydromethanolic extract and chromatographic fractions. The extract was fractionated on silica gel, and the resulting fractions were combined according to thin\u2010layer chromatography (TLC) profiles. Active fractions were characterized by high\u2010performance liquid chromatography\u2013high\u2010resolution tandem mass spectrometry (HPLC\u2013HRMS\/MS). Antioxidant activity was assessed using 2,2\u2010diphenyl\u20101\u2010picrylhydrazyl (DPPH), ferric reducing power, and \u03b2\u2010carotene bleaching assays, while anti\u2010protein denaturation was tested via heat\u2010induced denaturation of bovine serum and egg albumins, with diclofenac as reference. Profiling revealed quinic, caffeoylquinic, caffeic, and rosmarinic acids, and luteolin and quercetin derivatives. Fraction 11 showed the strongest antioxidant effect, comparable to butylated hydroxytoluene (BHT), while fraction 8 showed the highest protein\u2010stabilizing activity. These findings highlight\n                    <jats:italic>A. mogadorensis<\/jats:italic>\n                    as a promising source of natural antioxidant and protein\u2010stabilizing agents and provide a phytochemical and in vitro basis consistent with its traditional use in Moroccan medicine.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503691","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T10:07:58Z","timestamp":1776247678000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phytochemical Profiling and In Vitro Antioxidant and Anti\u2010Protein Denaturation Activities of Bioactive Fractions From the Moroccan Endemic\n                    <i>Andryala 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