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Their structures and absolute configurations were elucidated by a comprehensive analysis of the spectroscopic data, including high\u2010resolution electrospray ionization mass spectrometry, infrared, nuclear magnetic resonance, X\u2010ray crystallography, and electronic circular dichroism data. Among them, compound\n                    <jats:bold>1<\/jats:bold>\n                    was the first example of an\n                    <jats:italic>ent<\/jats:italic>\n                    \u2010atisane diterpenoid with an\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010oriented hydroxyl group at C\u20107. In addition, the cytotoxicity of all the isolated\n                    <jats:italic>ent<\/jats:italic>\n                    \u2010atisane diterpenoids was evaluated against human cervical carcinoma, human acute promyelocytic leukemia, and human hepatoma cell lines. Compound\n                    <jats:bold>3<\/jats:bold>\n                    demonstrated significant cytotoxic activity against the selected cell lines with an IC\n                    <jats:sub>50<\/jats:sub>\n                    value from 7.5 to 10.1 \u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202503775","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T10:48:42Z","timestamp":1767869322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>ent<\/i>\n                    \u2010Atisane Diterpenoids From\n                    <i>Euphorbia micractina<\/i>\n                    and Their Cytotoxic Activity"],"prefix":"10.1002","volume":"23","author":[{"given":"Yang\u2010Cuo","family":"Banma","sequence":"first","affiliation":[{"name":"Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy Qinghai Nationalities University  Xining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Lian","family":"Wen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering Lanzhou University  Lanzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ao","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering Lanzhou University  Lanzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao\u2010Nan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy Qinghai Nationalities University  Xining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy Qinghai Nationalities University  Xining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng\u2010Cheng","family":"Lin","sequence":"additional","affiliation":[{"name":"Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy Qinghai Nationalities University  Xining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5937-5569","authenticated-orcid":false,"given":"Jian\u2010Jun","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy Qinghai Nationalities University  Xining China"},{"name":"State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering Lanzhou University  Lanzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Xing Hua Ben Cao Gang Yao","author":"Wu Z. 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