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Their structures were elucidated through comprehensive spectroscopic analysis, including MS, UV, IR, and 1D\/2D NMR and quantum chemical calculations of electronic circular dichroism (ECD). In bioactivity evaluation, all isolates were evaluated for their inhibition effects on nitric oxide (NO) production in lipopolysaccharide (LPS)\u2010induced RAW 264.7 macrophage cells. Among them, compounds\n                    <jats:bold>1<\/jats:bold>\n                    and\n                    <jats:bold>2<\/jats:bold>\n                    exhibited significant inhibition of NO release, with IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 8.38 \u00b1 0.06 \u00b5M and 10.27 \u00b1 0.68 \u00b5M, respectively.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71205","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T19:44:22Z","timestamp":1776714262000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Five New Sesquiterpenoids From the Fruits of\n                    <i>Torilis japonica<\/i>\n                    With Nitric Oxide Inhibitory Activity"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0527-8513","authenticated-orcid":false,"given":"Yan\u2010Jing","family":"Zhang","sequence":"first","affiliation":[{"name":"Jinan University  Guangzhou P. R. China"},{"name":"Department of Anesthesiology The Eighth Affiliated Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan) Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao\u2010Chun","family":"Zhan","sequence":"additional","affiliation":[{"name":"Jinan University  Guangzhou P. R. China"},{"name":"Department of Anesthesiology The Eighth Affiliated Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan) Foshan China"},{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment and Institute of Traditional Chinese Medicine &amp; Natural Products College of Pharmacy Jinan University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian\u2010Hui","family":"He","sequence":"additional","affiliation":[{"name":"Jinan University  Guangzhou P. R. China"},{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment and Institute of Traditional Chinese Medicine &amp; Natural Products College of Pharmacy Jinan University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Ting","family":"Weng","sequence":"additional","affiliation":[{"name":"Jinan University  Guangzhou P. R. China"},{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment and Institute of Traditional Chinese Medicine &amp; Natural Products College of Pharmacy Jinan University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Jinan University  Guangzhou P. R. 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