{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:14:44Z","timestamp":1783368884683,"version":"3.54.6"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42506089"],"award-info":[{"award-number":["42506089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Eight new myrochromanol derivatives (\n                    <jats:bold>1<\/jats:bold>\n                    \u2010\n                    <jats:bold>5<\/jats:bold>\n                    ,\n                    <jats:bold>7<\/jats:bold>\n                    \u2010\n                    <jats:bold>9<\/jats:bold>\n                    ), together with two known analogues (\n                    <jats:bold>6<\/jats:bold>\n                    ,\n                    <jats:bold>10<\/jats:bold>\n                    ), were isolated from the marine\u2010derived fungal\u2010bacterial symbiont\n                    <jats:italic>Albifimbria verrucaria<\/jats:italic>\n                    \/\n                    <jats:italic>Burkholderia territorii<\/jats:italic>\n                    GXIMD 14478. Their structures with absolute configurations were determined through extensive spectroscopic data, circular dichroism (CD) spectroscopy, quantum chemical calculations, and chemical modifications. Notably, compounds\n                    <jats:bold>1<\/jats:bold>\n                    \u2010\n                    <jats:bold>2<\/jats:bold>\n                    possessed rare 6\/6\/6 and 6\/6\/5 tricyclic benzopyran skeletons, respectively. In bioassays, compound\n                    <jats:bold>6<\/jats:bold>\n                    exhibited cytotoxicity against RAW264.7 macrophages (83.3% inhibition of cell viability at 20\u00a0\u00b5M), while other compounds showed no notable cytotoxic effects. Compounds\n                    <jats:bold>8<\/jats:bold>\n                    and\n                    <jats:bold>9<\/jats:bold>\n                    inhibited lipopolysaccharide (LPS)\u2010induced nitric oxide (NO) production in RAW264.7 macrophages. This study expands the structural diversity of myrochromanols from marine fungal\u2010bacterial symbionts and underscores their potential for bioactive metabolite discovery.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71297","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T06:03:09Z","timestamp":1781244189000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eight New Myrochromanol Derivatives From a Marine Fungal\u2010Bacterial Symbiont"],"prefix":"10.1002","volume":"23","author":[{"given":"Xiao\u2010Yan","family":"Li","sequence":"first","affiliation":[{"name":"Faculty of Pharmacy\/Institute of Marine Drugs Guangxi University of Chinese Medicine  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei\u2010Hua","family":"Yao","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy\/Institute of Marine Drugs Guangxi University of 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