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Among them, three are previously unreported, including two coumarinolignans (artenujianenins A and B,\n                    <jats:bold>1<\/jats:bold>\n                    and\n                    <jats:bold>2<\/jats:bold>\n                    ) and one benzofuran neolignan (artenujianenin C,\n                    <jats:bold>3<\/jats:bold>\n                    ). Through chiral separation, a pair of enantiomers (\u00b1)\u2010\n                    <jats:bold>1<\/jats:bold>\n                    \u00a0was obtained, whereas compounds\u00a0\n                    <jats:bold>2<\/jats:bold>\n                    \u00a0and\u00a0\n                    <jats:bold>3<\/jats:bold>\n                    \u00a0were not resolved due to insufficient material. The structures of all isolates were established by comprehensive spectroscopic analysis, and the absolute configurations of (\u00b1)\n                    <jats:bold>1<\/jats:bold>\n                    were assigned based on electronic circular dichroism (ECD) calculations. This study marks the first isolation of phenolic compounds from this species, expanding its chemical diversity beyond the previously reported sesquiterpenoids. In bioactivity evaluations,\u00a0compound\n                    <jats:bold>4<\/jats:bold>\n                    showed significant anti\u2010inflammatory activity (IC\n                    <jats:sub>50<\/jats:sub>\n                    = 8.09 \u00b1 0.18 \u00b5M) and down\u2010regulated\n                    <jats:italic>IL<\/jats:italic>\n                    \u2010\n                    <jats:italic>1\u03b2<\/jats:italic>\n                    expression. None of the tested compounds, however, exhibited cytotoxicity against the human cancer cell lines A549, HeLa, HepG2, and Huh\u20107 at concentrations up to 20.00 \u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71349","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T17:21:01Z","timestamp":1779384061000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phenolic Compounds From\n                    <i>Artemisia nujianensis<\/i>\n                    and Their Anti\u2010Inflammatory Activities"],"prefix":"10.1002","volume":"23","author":[{"given":"Qiao\u2010Long","family":"Hao","sequence":"first","affiliation":[{"name":"School of Pharmacy Shandong Second Medical University  Weifang People's Republic of China"},{"name":"Shandong Laboratory of Yantai Drug Discovery Bohai Rim Advanced Research Institute For Drug Discovery  Yantai People's Republic of 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