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E2A1, together with a new sesquiterpene\u2010shikimate\u2010conjugated spirocyclic meroterpene, named capitalensis E (\n                    <jats:bold>3<\/jats:bold>\n                    ). The structures of\n                    <jats:bold>1\u20133<\/jats:bold>\n                    were elucidated by nuclear magnetic resonance spectroscopy (NMR), high\u2010resolution electrospray ionization mass spectrometry (HR\u2010ESI\u2010MS), single\u2010crystal x\u2010ray diffraction analysis, electronic circular dichroism (ECD) calculations, and modified Mosher's method. Compounds\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>3<\/jats:bold>\n                    were evaluated for their inhibitory effects on nitric oxide (NO) production in lipopolysaccharide (LPS)\u2010stimulated RAW264.7 cells. Among them, compound\n                    <jats:bold>2<\/jats:bold>\n                    exhibited inhibitory activity with an IC\n                    <jats:sub>50<\/jats:sub>\n                    value of 10.8\u00a0\u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71368","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T05:39:46Z","timestamp":1779687586000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three Meroterpenes From the Mangrove Endophytic Fungus\n                    <i>Phyllosticta<\/i>\n                    sp. E2A1"],"prefix":"10.1002","volume":"23","author":[{"given":"Mei","family":"Wang","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang\u2010Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi\u2010Kang","family":"Zheng","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Natural Drugs Research and Development School of Pharmacy The First Dongguan Affiliated Hospital, Guangdong Medical University  Dongguan China"},{"name":"Dongguan Key Laboratory for Marine Innovative Drugs and Bioproducts Guangdong Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Shen","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Natural Drugs Research and Development School of Pharmacy The First Dongguan Affiliated Hospital, Guangdong Medical University  Dongguan China"},{"name":"Dongguan Key Laboratory for Marine Innovative Drugs and Bioproducts Guangdong Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Wen","family":"Tian","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0807-5229","authenticated-orcid":false,"given":"Jun","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Southern Medical University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Natural Drugs Research and Development School of Pharmacy The First Dongguan Affiliated Hospital, Guangdong Medical University  Dongguan China"},{"name":"Dongguan Key Laboratory for Marine Innovative Drugs and Bioproducts Guangdong Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112860"},{"key":"e_1_2_9_3_1","first-page":"560","article-title":"Secondary Metabolites from Mangrove\u2010Associated Fungi: Source, Chemistry and Bioactivities","volume":"39","author":"Chen S.","year":"2022","journal-title":"Journal of Natural Products"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b04020"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b04648"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/md10091993"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/np4005757"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.112860"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.103968"},{"key":"e_1_2_9_10_1","first-page":"856","article-title":"Secondary Metabolites of Endophytic Guignardia Mangiferae From Smilax glabra and Their Antitumor Activities","volume":"43","author":"Liang F. 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