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Rich in phenolics and carotenoids, it shows strong antioxidant activity (notably in DPPH) and high SPF\u2010related UV protection. Major compounds include rosmarinic acid, hydroxybenzoic acid, quercetin, and luteolin. Synergistic interactions among bioactives enhance antioxidant capacity beyond that of individual compounds. The extract demonstrates pronounced anti\u2010inflammatory effects against platelet\u2010activating factor (PAF), exceeding those of isolated standards, while showing lower activity against ADP\u2010induced platelet aggregation, indicating specificity toward PAF\u2010mediated pathways. Molecular docking supports interactions with the PAF receptor. Given PAF's role in UV\u2010induced inflammation and melanoma, the extract's UV absorption, antioxidant capacity, and anti\u2010PAF activity suggest protective effects against photoaging. Antimicrobial activity is stronger against Gram\u2010negative bacteria, with slower effects on Gram\u2010positive strains. Overall,\n                    <jats:italic>R. rubiginosa<\/jats:italic>\n                    extract exhibits broad bioactivity, supporting its potential as a multifunctional ingredient in functional foods, nutraceuticals, supplements, and cosmetic formulations.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71418","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T19:37:28Z","timestamp":1781552248000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Rosa rubiginosa L<\/i>\n                    . 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