{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:14:26Z","timestamp":1783368866201,"version":"3.54.6"},"reference-count":48,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100006701","name":"Umm Al-Qura University","doi-asserted-by":"publisher","award":["26UQU4280406GSSR05"],"award-info":[{"award-number":["26UQU4280406GSSR05"]}],"id":[{"id":"10.13039\/501100006701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Five carbonyl thiacalixarene derivatives (\n                    <jats:bold>5, 6, 7, 9,<\/jats:bold>\n                    and\n                    <jats:bold>10<\/jats:bold>\n                    ) were synthesized via the reactions of mono\u2010substituted thiacalixarenes (\n                    <jats:bold>2, 3, 4,<\/jats:bold>\n                    and\n                    <jats:bold>8<\/jats:bold>\n                    ) with ethyl bromoacetate, 2\u2010chloro\u2010N\u2010(\n                    <jats:italic>p<\/jats:italic>\n                    \u2010tolyl)acetamide, or 2\u2010chloro\u2010\n                    <jats:italic>N<\/jats:italic>\n                    \u2010(\n                    <jats:italic>p<\/jats:italic>\n                    \u2010tolyl)ethanethioamide. The chemical structure of the synthesized compounds was confirmed by IR and NMR spectroscopy. The metal ion recognition abilities of these thiacalixarene derivatives were investigated through liquid\u2010liquid extraction of various metal picrates (Na\n                    <jats:sup>+<\/jats:sup>\n                    , K\n                    <jats:sup>+<\/jats:sup>\n                    , Cs\n                    <jats:sup>+<\/jats:sup>\n                    , Ag\n                    <jats:sup>+<\/jats:sup>\n                    , Pb\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , Cd\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , Co\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , Ni\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , Cu\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , and Hg\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    ) from water to dichloromethane. Compounds\n                    <jats:bold>5<\/jats:bold>\n                    and\n                    <jats:bold>6<\/jats:bold>\n                    exhibited poor to moderate extraction efficiencies, likely due to the limited number of carbonyl groups. In contrast, compounds\n                    <jats:bold>7, 9<\/jats:bold>\n                    , and\n                    <jats:bold>10<\/jats:bold>\n                    showed moderate to high extraction capacities, with thiacalixarene\n                    <jats:bold>9<\/jats:bold>\n                    demonstrating the highest extraction of Cs\n                    <jats:sup>+<\/jats:sup>\n                    (93.4%) and strong extraction of other metal ions, highlighting the effect of carbonyl\u2010to\u2010thionyl conversion on metal\u2010ligand interactions. The insecticidal activities of the synthesized thiacalixarene derivatives in combination with the commercial insecticide chlorfenapyr were evaluated against the second and fourth larval instars of\n                    <jats:italic>Spodoptera littoralis<\/jats:italic>\n                    . Mortality was recorded 72 h post\u2010treatment, and LC\n                    <jats:sub>50<\/jats:sub>\n                    values were determined. These results indicate that calixarene derivatives can enhance pesticide efficiency and offer a promising strategy for designing next\u2010generation agrochemical agents.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71428","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T19:43:11Z","timestamp":1781552591000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Functionalized Thiacalix[4]arenes as Dual Metal\u2010Ion Extractants and Insecticidal Agents: Synthesis, Characterization, and Insecticidal Activity Against\n                    <i>Spodoptera littoralis<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Munirah M.","family":"Al\u2010Rooqi","sequence":"first","affiliation":[{"name":"Department of Chemistry Faculty of Science Umm Al\u2010Qura University  Makkah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Sharaf","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Sohag University  Sohag Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israa J.","family":"Hakeem","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences College of Science University of Jeddah  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed S.","family":"Samman","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Taibah University  Madina Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr H.","family":"Moustafa","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Sohag University  Sohag Egypt"},{"name":"Faculty of Science King Salman International University  Ras Sudr Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounir A. A.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Sohag University  Sohag Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7850-7520","authenticated-orcid":false,"given":"Mohamed A.","family":"Gad","sequence":"additional","affiliation":[{"name":"Agriculture Research Center Research Institute of Plant Protection  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1704-6051","authenticated-orcid":false,"given":"Ali M.","family":"Drar","sequence":"additional","affiliation":[{"name":"Agriculture Research Center Research Institute of Plant Protection  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman A.","family":"Alsimaree","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science and Humanities Shaqra University  Shaqra Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad","family":"Moussa","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science United Arab Emirates University  UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Abd\u2010El\u2010Aziz","sequence":"additional","affiliation":[{"name":"College of Materials Science and Chemical Engineering Harbin Engineering University  Harbin China"},{"name":"Qingdao Innovation and Development Center Harbin Engineering University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9890-2114","authenticated-orcid":false,"given":"Omran A.","family":"Omran","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Sohag University  Sohag Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2364-0380","authenticated-orcid":false,"given":"Saleh A.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Umm Al\u2010Qura University  Makkah Saudi Arabia"},{"name":"Chemistry Department Faculty of Science Assiut University  Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.200990325"},{"key":"e_1_2_11_3_1","first-page":"234","article-title":"From Resinous Tar to Molecular Basket","volume":"68","author":"Gutsche C. 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