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(Lauraceae), a well\u2010known traditional Chinese medicinal plant. Infections caused by\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    have become a serious clinical concern due to the increasing emergence of drug resistance and the shortage of highly selective antifungal agents. Lindenane\u2010type sesquiterpenoids are characteristic constituents of\n                    <jats:italic>L. aggregata<\/jats:italic>\n                    with diverse structures and a broad spectrum of biological activities; however, their antifungal potential has rarely been explored. Their structures were elucidated by comprehensive spectroscopic analyses and ECD calculations. In the antimicrobial assay, compounds\n                    <jats:bold>1\u20136<\/jats:bold>\n                    ,\n                    <jats:bold>8<\/jats:bold>\n                    ,\n                    <jats:bold>12<\/jats:bold>\n                    , and\n                    <jats:bold>14<\/jats:bold>\n                    exhibited selective and potent inhibitory activity against\n                    <jats:italic>C. albicans<\/jats:italic>\n                    , with MIC values ranging from 4\u20108 \u00b5g\/mL, whereas they exhibited weak or no antibacterial effects. This study expands the structural diversity of lindenane\u2010type sesquiterpenoids and offers new antifungal lead scaffolds from a natural source.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71483","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:07:20Z","timestamp":1783368440000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three New Lindenane Sesquiterpenoids From\n                    <i>Lindera aggregata<\/i>\n                    With Selective Antifungal Activity"],"prefix":"10.1002","volume":"23","author":[{"given":"Huawei","family":"Lv","sequence":"first","affiliation":[{"name":"College of Pharmaceutical Science &amp; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang Key Laboratory of Green Low\u2010Carbon, and Efficient Development of Marine Fishery Resources Zhejiang University of Technology  Hangzhou China"},{"name":"School of Pharmacy Youjiang Medical University for Nationalities  Baise PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaona","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Science &amp; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang Key Laboratory of Green Low\u2010Carbon, and Efficient Development of Marine Fishery Resources Zhejiang University of Technology  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengdi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Analysis and Testing Center Zhejiang University of Technology  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongbo","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Pharmacy Youjiang Medical University for Nationalities  Baise PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Emam","sequence":"additional","affiliation":[{"name":"Department of Phytochemistry and Plant Systematics National Research Centre Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Science &amp; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang Key Laboratory of Green Low\u2010Carbon, and Efficient Development of Marine Fishery Resources Zhejiang University of Technology  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3567-7287","authenticated-orcid":false,"given":"Xing\u2010Nuo","family":"Li","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Science &amp; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang Key Laboratory of Green Low\u2010Carbon, and Efficient Development of Marine Fishery Resources Zhejiang University of Technology  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.48130\/MPB-2023-0011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116954"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.1071276"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2025.114477"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2053"},{"key":"e_1_2_9_7_1","first-page":"75","article-title":"Herbal Textual Research on Linderae Radix in Famous Classical Formulas","volume":"29","author":"Cheng F.","year":"2023","journal-title":"Chinese Journal of Experimental Traditional"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2023.113866"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jointm.2024.01.005"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v12.i16.2686"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2025.114452"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/vjch.201800077"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/np500951s"},{"key":"e_1_2_9_14_1","first-page":"339","article-title":"Seven New Sesquiterpene Lactones From Lindera Aggregata","volume":"31","author":"Chou G.\u2010X.","year":"2000","journal-title":"Journal of China Pharmaceutical University"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-020-03089-w"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/md9091534"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.112924"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26010042"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(93)85167-P"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1270922"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15122673"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prmcm.2023.100262"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.4c00690"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/chir.22138"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42995-023-00170-5"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.521"}],"container-title":["Chemistry &amp; 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