{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T13:05:29Z","timestamp":1785330329044,"version":"3.55.0"},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Natural bioactive compounds have emerged as essential candidates for pharmaceutical development due to their high efficacy and low toxicity. Hence, this study was designed to evaluate how varying sowing dates and nitrogen treatments influence the phytochemical profile and biological activity of\n                    <jats:italic>Ricinus communis<\/jats:italic>\n                    L. Quantitative LC\u2013MS\/MS profiling of the aerial parts established quinic acid (94.789\u00a0mg\/g), ellagic acid (39.955\u00a0mg\/g), and gallic acid (35.732\u00a0mg\/g) as the major phenolic\u2010flavonoid compounds in the extract. The extracts exhibited strong antioxidant potential, with determined values of 37.35 \u00b1 0.32\u00a0\u00b5g\/mL (DPPH IC\n                    <jats:sub>50<\/jats:sub>\n                    ), 13.05 \u00b1 0.08\u00a0\u00b5g\/mL (ABTS IC\n                    <jats:sub>50<\/jats:sub>\n                    ), and 30.93 \u00b1 0.56\u00a0\u00b5g\/mL (CUPRAC A\n                    <jats:sub>0<\/jats:sub>\n                    .\n                    <jats:sub>5<\/jats:sub>\n                    ). Enzymatic assays revealed tissue\u2010specific inhibition, with the aerial parts targeting urease (66.44% \u00b1 0.67%) and collagenase (47.61% \u00b1 0.82%), and the seeds predominantly affecting \u03b1\u2010glucosidase (97.12% \u00b1 1.69%) and AChE (55.37% \u00b1 0.89%). In conclusion, this study bridges agronomy and pharmacology by demonstrating that sowing dates and nitrogen treatments determine phytochemical yield. Furthermore, it reveals a novel, tissue\u2010specific divergence, as the aerial parts and seeds of\n                    <jats:italic>R. communis<\/jats:italic>\n                    target completely distinct enzymatic pathways.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71495","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:55:53Z","timestamp":1784130953000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tissue\u2010Specific Phytochemical Profiling and Bioactivity of\n                    <i>Ricinus communis<\/i>\n                    L. Under Varying Agronomic Conditions"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9310-7491","authenticated-orcid":false,"given":"Yunus","family":"Guzel","sequence":"first","affiliation":[{"name":"Department of Field Crops Faculty of Agriculture University of Dicle  Diyarbak\u0131r T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8844-4751","authenticated-orcid":false,"given":"Sema","family":"Basbag","sequence":"additional","affiliation":[{"name":"Department of Field Crops Faculty of Agriculture University of Dicle  Diyarbak\u0131r T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5196-3892","authenticated-orcid":false,"given":"Abbas","family":"Tarhan","sequence":"additional","affiliation":[{"name":"Dicle University Science and Technology Application and Research Center  Diyarbakir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0988-9462","authenticated-orcid":false,"given":"Ismail","family":"Yener","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry Faculty of Pharmacy University of Dicle  Diyarbakir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.12980\/apjtb.4.201414b16"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2008.08.020"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/625961"},{"issue":"2","key":"e_1_2_9_5_1","first-page":"229","article-title":"In\u2010Vitro Antioxidant Activity of the Successive Extracts of R. communis Leaves","volume":"1","author":"Gupta M. 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