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The synthesized compounds were evaluated for their antimicrobial, antioxidant, and anti\u2010inflammatory activities. Among the tested derivatives, compound\n                    <jats:bold>5c<\/jats:bold>\n                    exhibited superior antibacterial activity compared with the standard drug chloramphenicol, while compounds\n                    <jats:bold>6b<\/jats:bold>\n                    and\n                    <jats:bold>6c<\/jats:bold>\n                    showed antifungal activity comparable to the reference drug fluconazole. Compounds\n                    <jats:bold>5c<\/jats:bold>\n                    and\n                    <jats:bold>8c<\/jats:bold>\n                    demonstrated antioxidant activity slightly higher than that of ascorbic acid. Molecular docking studies were performed to predict the binding affinities toward inflammatory target proteins, supporting the observed biological data. Compound\n                    <jats:bold>8b<\/jats:bold>\n                    exhibited the highest anti\u2010inflammatory activity among the tested derivatives, though slightly lower than celecoxib. The results suggest that benzo[d]azole\u2010linked heterocycles represent promising scaffolds for further development of multifunctional bioactive agents.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71507","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T18:52:16Z","timestamp":1785178336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Synthesis of Benzazolyl Oxadiazolyl\/Thiadiazolyl\/Triazolyl Amines and Their Antimicrobial, Antioxidant, In Silico and In Vivo Anti\u2010Inflammatory Activities"],"prefix":"10.1002","volume":"23","author":[{"given":"Kalyani","family":"Madduru","sequence":"first","affiliation":[{"name":"Department of Chemistry Sri Venkateswara University  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Sowmya","family":"Donthamsetty","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Sri Padmavati Mahila Visvavidyalayam  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4703-0939","authenticated-orcid":false,"given":"Shaheen","family":"Begum","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Technology Sri Padmavati Mahila Visvavidyalayam  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmavathi","family":"Venkatapuram","sequence":"additional","affiliation":[{"name":"Department of Chemistry Sri Venkateswara University  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"e_1_2_19_2_1","first-page":"9503","article-title":"Recent Advances: Heterocycles in Drugs and Drug Discovery","volume":"25","author":"Ivana P.","year":"2025","journal-title":"International Journal of Molecular Sciences"},{"issue":"2","key":"e_1_2_19_3_1","article-title":"Recent Advances in the Green Synthesis and Biological Application of 2\u2010Substituted Benzazoles","volume":"1349","author":"Abdel M. 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