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Their structures were elucidated using NMR, HR\u2010ESI\u2010MS, ECD, and single\u2010crystal x\u2010ray diffraction. Compounds\n                    <jats:bold>2\u20137<\/jats:bold>\n                    exhibited anti\u2010inflammatory activity by inhibiting NO production and reducing the levels of the proinflammatory TNF\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    and IL\u20106 in LPS\u2010induced RAW264.7 macrophages. The structure\u2013activity relationship of compounds\n                    <jats:bold>1\u20137<\/jats:bold>\n                    was preliminarily assessed. The findings from this study highlight the potential of ellagitannins from\n                    <jats:italic>Euryale<\/jats:italic>\n                    shells as anti\u2010inflammatory agents and provide a chemical basis for further functional studies. Moreover, this study enriches the material basis of the shells of\n                    <jats:italic>E. ferox<\/jats:italic>\n                    Salisb.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71512","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T18:12:28Z","timestamp":1785089548000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ellagitannins From the Seed Coat of\n                    <i>Euryale ferox<\/i>\n                    and Their Inhibitory Effects on LPS\u2010Induced Inflammation in RAW264.7 Cells"],"prefix":"10.1002","volume":"23","author":[{"given":"Meng\u2010Ting","family":"Ren","sequence":"first","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan\u2010Xia","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u2010Zhong","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"},{"name":"Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010Su","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"},{"name":"Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu\u2010Xi","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"},{"name":"Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010Shuo","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De\u2010Ling","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"},{"name":"Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces  Hefei China"},{"name":"Anhui Province Key Laboratory of Bioactive Natural Products  Hefei China"},{"name":"Bozhou University  Bozhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng\u2010Qing","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei China"},{"name":"Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces  Hefei China"},{"name":"Anhui Province Key Laboratory of Bioactive Natural Products  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"K. 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