{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T13:05:10Z","timestamp":1785330310860,"version":"3.55.0"},"reference-count":63,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Bauhinia purpurea<\/jats:italic>\n                    , a widespread and common plant possessing good antioxidant and anti\u2010inflammatory properties, serves as an excellent precursor for green nanomaterial synthesis. Plant\u2010derived carbon quantum dots (CQDs) often retain the therapeutic traits of their source, enhancing biomedical relevance. In this study,\n                    <jats:italic>B. purpurea<\/jats:italic>\n                    \u2010derived nitrogen\u2010doped CQDs (BPN\u2010CQDs) were synthesized via a green microwave\u2010assisted carbonization method. EDX and FTIR analyses verified nitrogen enrichment and surface functionalization. UV\u2013vis spectroscopy revealed peaks at 287, 325, and 370\u00a0nm, an absorption edge at 460\u00a0nm, and a direct bandgap energy of 3.44\u00a0eV. Fluorescence studies showed peak emission near 440\u00a0nm upon 320\u00a0nm excitation with redshifting at higher wavelengths. TEM and DLS analyses confirmed spherical morphology with a mean size of 3.6 \u00b1 0.2\u00a0nm and a multimodal distribution. BPN\u2010CQDs showed anti\u2010arthritic and anti\u2010inflammatory activity in SW982 cells, enhancing wound closure by 30.36% at 500\u00a0\u00b5g mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    versus 11.43% in controls. They exhibited good biocompatibility (IC\n                    <jats:sub>50<\/jats:sub>\n                    = 1821\u00a0\u00b5g mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) and inhibited protein denaturation (IC\n                    <jats:sub>50<\/jats:sub>\n                    = 546.3\u00a0\u00b5g mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) and COX\u20102 activity (IC\n                    <jats:sub>50<\/jats:sub>\n                    = 470.9\u00a0\u00b5g mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) dose\u2010dependently. Cytokine levels of interleukin\u20101 beta (IL\u20101\u03b2) and tumor necrosis factor\u2010alpha (TNF\u2010\u03b1) were significantly reduced. These findings highlight the therapeutic potential of BPN\u2010CQDs in arthritis management through their biocompatibility and combined anti\u2010inflammatory and wound\u2010healing actions.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71549","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T18:13:02Z","timestamp":1785089582000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["N\u2010Doped Carbon Quantum Dots From\n                    <i>Bauhinia purpurea<\/i>\n                    With Anti\u2010Inflammatory and Wound\u2010Healing Properties"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5659-5320","authenticated-orcid":false,"given":"Bothe","family":"Thokchom","sequence":"first","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6813-8952","authenticated-orcid":false,"given":"Santosh Mallikarjun","family":"Bhavi","sequence":"additional","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2411-0931","authenticated-orcid":false,"given":"Akshata Choudhari","family":"Padti","sequence":"additional","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1468-464X","authenticated-orcid":false,"given":"Sapam Riches","family":"Singh","sequence":"additional","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2535-9442","authenticated-orcid":false,"given":"Megha B.","family":"Abbigeri","sequence":"additional","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudheendra Rao","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Drosophila and Nano\u2010biomedicine Research Laboratory Department of Applied Genetics Karnatak University  Dharwad Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalini","family":"Moses","sequence":"additional","affiliation":[{"name":"Centre of Applied Genetics Bangalore University  Bangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shri Lakshmi","family":"S. 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