{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:22Z","timestamp":1788858562907,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study evaluated how geographical origin (El Alamein vs. Red Sea regions in Egypt) and extraction methods saffect the chemical profile and antimicrobial efficacy of\n                    <jats:italic>Cotula cinerea<\/jats:italic>\n                    essential oils. Comparing conventional hydro\u2010distillation (HD) to microwave\u2010assisted extraction (MAE), researchers found that MAE delivered higher oil yields (0.35%\u20130.37%) than HD (0.31%\u20130.34%) in significantly less time. Gas chromatography\u2010mass spectrometry (GC\/MS) identified 19 volatile compounds\u2014predominantly oxygenated monoterpenes like pinocarvone, \u03b1\u2010thujone, and camphene\u2014with statistical analyses confirming that both location and extraction technique distinctly altered this chemical composition. Furthermore, MAE\u2010extracted oils demonstrated superior antimicrobial activity, particularly those from El Alamein, which reached a notable 25\u00a0mm inhibition zone against Aspergillus niger. Ultimately, the results indicate that MAE is a highly efficient and reproducible method for harvesting bioactive\n                    <jats:italic>C. cinerea<\/jats:italic>\n                    oils for potential pharmaceutical and nutraceutical applications.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71584","type":"journal-article","created":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T10:57:08Z","timestamp":1786273028000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Geographical Location and Extraction Methods on the Chemical Composition and Antimicrobial Activity of\n                    <i>Cotula cinerea<\/i>\n                    Essential Oil via Chemo\u2010Metric Analysis"],"prefix":"10.1002","volume":"23","author":[{"given":"Sherin K.","family":"Ali","sequence":"first","affiliation":[{"name":"Chemistry of Medicinal Plants Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6851-7650","authenticated-orcid":false,"given":"Ibrahim A.","family":"Saleh","sequence":"additional","affiliation":[{"name":"Chemistry of Medicinal Plants Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abd El\u2010Nasser G.","family":"El\u2010Gendy","sequence":"additional","affiliation":[{"name":"Medicinal and Aromatic Plants Research Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer A. Abd El","family":"Aty","sequence":"additional","affiliation":[{"name":"Chemistry of Natural &amp; Microbial Products Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1639-3518","authenticated-orcid":false,"given":"Tarik A.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Chemistry of Medicinal Plants Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed\u2010Elamir F.","family":"Hegazy","sequence":"additional","affiliation":[{"name":"Chemistry of Medicinal Plants Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,9]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","first-page":"46","article-title":"Therapeutic Potential of Medicinal Plants: A Review","volume":"1","author":"Kumar S.","year":"2015","journal-title":"Journal of Biological and Chemical Chronicles"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo9110258"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28041845"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2021.08.001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph16111615"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/soc14090187"},{"key":"e_1_2_8_8_1","volume-title":"Flora of Egypt. 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