{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:23Z","timestamp":1788858563138,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T00:00:00Z","timestamp":1786147200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82460693"],"award-info":[{"award-number":["82460693"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22267001"],"award-info":[{"award-number":["22267001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32360107"],"award-info":[{"award-number":["32360107"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012659","name":"Foundation for Innovative Research Groups of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Six new bergamotene sesquiterpenoids (\n 1<\/jats:bold>\n \u2013\n 6<\/jats:bold>\n ), one new cyclohexenone derivative (\n 7<\/jats:bold>\n ), and nine known compounds (\n 8<\/jats:bold>\n \u2013\n 16<\/jats:bold>\n ) were isolated from\n Citrus reticulata<\/jats:italic>\n \u2010associated endophytic fungus\n Aspergillus fumigatus<\/jats:italic>\n . The structures were systematically established mainly by NMR data, HRESIMS, DP4+ analysis, and ECD calculations. Compounds\n 2<\/jats:bold>\n \u2013\n 6<\/jats:bold>\n were proposed to be derived from \u03b2\u2010\n trans<\/jats:italic>\n \u2010bergamotene via C\u20105\/C\u20106 skeletal cleavage and further modifications. Among them, compounds\n 2<\/jats:bold>\n and\n 3<\/jats:bold>\n represent the first reported instances of the \u03b2\u2010bergamotene derivatives bearing an epoxide moiety, characterized by unique 6\/5\/3 and 6\/6\/3 tricyclic frameworks based on oxabicyclo[3.2.1]octane and oxabicyclo[3.3.1]nonane cores, respectively. Antifungal activities against two citrus pathogens,\n Fusarium graminearum<\/jats:italic>\n and\n Alternaria alternata<\/jats:italic>\n , revealed that most compounds exhibited\u00a0significant antifungal activities, with MIC values of 1\u20138 \u00b5g\/mL. Notably, the antifungal activities of compounds\n 8<\/jats:bold>\n and\n 9<\/jats:bold>\n against\n A. alternata<\/jats:italic>\n and compound\n 14<\/jats:bold>\n against\n F. graminearum<\/jats:italic>\n were comparable to those of nystatin.\n <\/jats:p>","DOI":"10.1002\/cbdv.71585","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T17:27:11Z","timestamp":1786210031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Metabolites Produced by\n Citrus reticulata<\/i>\n \u2010Derived Endophyte\n Aspergillus fumigatus<\/i>\n as Potential Antifungal Agents Against Citrus Pathogens"],"prefix":"10.1002","volume":"23","author":[{"given":"Wen\u2010Zhi","family":"Shi","sequence":"first","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"},{"name":"Institute of International Rivers and Eco\u2010Security Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng\u2010Shuang","family":"Wei","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan\u2010Liang","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Xue","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5509-4559","authenticated-orcid":false,"given":"Ya\u2010Bin","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue\u2010Qiong","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong\u2010Tao","family":"Ding","sequence":"additional","affiliation":[{"name":"Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology Yunnan University Kunming P. R. China"},{"name":"Institute of International Rivers and Eco\u2010Security Yunnan University Kunming P. R. China"},{"name":"Yunnan Key Laboratory of Chinese Medicine Processing, College of Chinese Materia Medica Yunnan University of Chinese Medicine Kunming P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/app12010029"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202100910"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750\u20103841.17576"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.71305"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42161\u2010023\u201001543\u20106"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/horticulturae8070612"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof11040263"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3114\/persoonia.2025.55.12"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS\u201007\u201022\u20101675\u2010PDN"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09603123.2022.2055748"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.06.069"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c08600"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.4c02769"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2023.135728"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021153"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253\u2010023\u201012657\u20103"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12934\u2010023\u201002118\u2010x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.113011"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA04290K"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202502414"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/md23100400"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.4c09030"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2022.105395"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/np8006793"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.6b00407"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.3c01175"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2023.2196722"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2022.113568"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13568\u2010017\u20100343\u2010z"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272\u2010010\u20100401\u20104"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.49.534"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2016.1269100"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5c07044"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2024.107438"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202401726"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202300004"}],"container-title":["Chemistry & Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71585","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.71585","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:31:08Z","timestamp":1788856268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.71585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/cbdv.71585"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.71585","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71585"}}