{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:08:59Z","timestamp":1788858539622,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104021"],"award-info":[{"award-number":["82104021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Two undescribed aspochalasins named amiaspochalasins I and J (\n 1<\/jats:bold>\n and\n 2<\/jats:bold>\n ), along with a known analogue named aspochalasin U (\n 3<\/jats:bold>\n ) were isolated from the endophytic fungus\n Aspergillus micronesiensis<\/jats:italic>\n . Their structures including absolute configurations were elucidated by extensive NMR data, molecular modelling studies, and electronic circular dichroism (ECD) calculations. Usually, there is a double bond at\n \u0394<\/jats:italic>\n 6<\/jats:sup>\n in the core structure of aspochalasins, while in compounds\n 1<\/jats:bold>\n \u2212\n 3<\/jats:bold>\n , this double bond has shifted to\n \u0394<\/jats:italic>\n 5<\/jats:sup>\n . Compound\n 1<\/jats:bold>\n is the first aspochalasin bearing a carbonyl at C\u20107, and compound\n 2<\/jats:bold>\n has an additional hydroxyl at C\u201017 in comparison of aspochalasin U (\n 3<\/jats:bold>\n ). Compounds\n 1<\/jats:bold>\n \u2212\n 3<\/jats:bold>\n showed moderate inhibitory effects on\n Staphylococcus aureus<\/jats:italic>\n ,\n Escherichia coli<\/jats:italic>\n , and\n Salmonella enterica<\/jats:italic>\n , and the MIC values of\n 1<\/jats:bold>\n \u2212\n 3<\/jats:bold>\n against\n Staphylococcus aureus<\/jats:italic>\n were 32, 64, and 64 \u00b5g mL\n \u22121<\/jats:sup>\n , respectively.\n <\/jats:p>","DOI":"10.1002\/cbdv.71594","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:42:18Z","timestamp":1786988538000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Amiaspochalasins I and J, Undescribed Aspochalasins with Antibacterial Activities From\n Aspergillus micronesiensis<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Zhaodi","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pharmacy The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhong","family":"Suo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongquan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmei","family":"Chen","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of Pharmacy Tongji Medical College Huazhong University of Science and Technology Wuhan P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7222-2142","authenticated-orcid":false,"given":"Yonghui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of Pharmacy Tongji Medical College Huazhong University of Science and Technology Wuhan P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Li","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of Pharmacy Tongji Medical College Huazhong University of Science and Technology Wuhan P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of Pharmacy Tongji Medical College Huazhong University of Science and Technology Wuhan P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6318-0091","authenticated-orcid":false,"given":"Hucheng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of Pharmacy Tongji Medical College Huazhong University of Science and Technology Wuhan P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/b903913a"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7NP00036G"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-59444-2_1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.9b00440"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2005.34"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2011.97"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2QO00309K"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/md12105124"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2011.12.021"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2014.04.009"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201200053"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2016.11.038"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b00919"}],"container-title":["Chemistry & Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71594","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.71594","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71594","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:26:51Z","timestamp":1788856011000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.71594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/cbdv.71594"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.71594","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71594"}}