{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:19Z","timestamp":1788858559035,"version":"build-2803163510"},"reference-count":60,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010627","name":"Southwest Forestry University","doi-asserted-by":"publisher","award":["LXXK\u20102025D15"],"award-info":[{"award-number":["LXXK\u20102025D15"]}],"id":[{"id":"10.13039\/501100010627","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Ageratina adenophora<\/jats:italic>\n                    (\n                    <jats:italic>A. adenophora<\/jats:italic>\n                    ) is a globally invasive plant with strong ecological adaptability. To elucidate its adaptive chemical basis and seasonal dynamics of bioactive constituents, this study used gas chromatography\u2013mass spectrometry (GC\u2013MS) and liquid chromatography\u2013mass spectrometry (LC\u2013MS) to analyze volatile oils and ethanol extracts from the aerial tissues of\n                    <jats:italic>A. adenophora<\/jats:italic>\n                    across four seasons. Partial least squares\u2010discriminant analysis (PLS\u2010DA) was applied to link seasonal metabolites with antioxidant and antibacterial activities. Essential oils contained monoterpenes and sesquiterpenes, peaking in summer (0.18%) and lowest in winter (0.08%). Monoterpenes dominated spring (28.67%), oxygenated sesquiterpenes autumn (40.81%). Major metabolites included three monoterpenes (o\u2010cymene, (+)\u20104\u2010carene, \u03b1\u2010phellandrene) and four sesquiterpenes (\u03b1\u2010bisabolol, germacrene D, aristolone, cubenol). Ethanol extracts had fluctuating phenolics, flavonoids, and tannins; flavonoids\/tannins peaked in spring, phenolics in summer. Summer samples showed the strongest antioxidant activity, autumn extracts optimal antimicrobial efficacy. PLS\u2010DA screened key active compounds: oil\u2010borne \u03b1\u2010terpinolene, \u03b1\u2010cadinol, and extract rosmarinic acid, rutin, which dominate dual bioactivities. This study clarifies seasonal composition\u2010bioactivity correlations in\n                    <jats:italic>A. adenophora<\/jats:italic>\n                    , supporting research on its invasion mechanisms and resource exploitation.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71603","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:34:30Z","timestamp":1787312070000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seasonal Variation in Chemical Constituents and Bioactivity of\n                    <i>Ageratina adenophora<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Ceqiong","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taijiao","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuli","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1970-870X","authenticated-orcid":false,"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7475-9614","authenticated-orcid":false,"given":"Haochen","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9652-0779","authenticated-orcid":false,"given":"Xiaohui","family":"Yan","sequence":"additional","affiliation":[{"name":"Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of Education Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun","family":"Hu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation in Southwest China (State Forestry Administration) Southwest Forestry University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2020.112600"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091064"},{"issue":"6","key":"e_1_2_10_4_1","first-page":"45","article-title":"Effects of Arbuscular Mycorrhizal Fungi on Plant Stress Resistance and Secondary Metabolite Synthesis","volume":"40","author":"Yuan H. 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