{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:02Z","timestamp":1788858542895,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The present study evaluated the biological activities and online HPLC\u2010DAD profiles of five extracts of\n                    <jats:italic>Capparis ovata<\/jats:italic>\n                    subsp.\n                    <jats:italic>canescens<\/jats:italic>\n                    prepared with ethyl acetate (EA), dichloromethane (DCM), ethanol, 70% ethanol\/water, and water. Online HPLC\u2010DAD with post\u2010column antioxidant detection was used to profile tentatively annotated antioxidant\u2010responsive metabolites at 280, 595, 517, 734, and 450\u00a0nm. Antioxidant activity was assessed using DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum (PBD), and metal\u2010chelating assays. Eight antioxidant\u2010responsive markers\u2014catechin, cinnamic acid, caffeic acid, \u03b3\u2010tocopherol, apigenin, quercetin\u20103\u2010O\u2010hexoside, myristoleic acid, and kaempferol\u20103\u2010O\u2010rutinoside\u2014were tentatively annotated from their chromatographic behavior, UV\u2010DAD characteristics, and post\u2010column antioxidant responses. Ethanol and ethanol\/water extracts showed the strongest DPPH (82.35\u201382.97\u00a0mg TE\/g), ABTS (93.68\u2013122.00\u00a0mg TE\/g), FRAP (98.46\u2013116.84\u00a0mg TE\/g), and CUPRAC (155.43\u2013205.02\u00a0mg TE\/g) activities. In the PBD assay, EA, ethanol, and DCM showed the highest activities (2.11\u20132.39\u00a0mmol TE\/g), with EA displaying the highest numerical value (2.39\u00a0\u00b1\u00a00.10\u00a0mmol TE\/g). These findings support further investigation of\n                    <jats:italic>C. ovata<\/jats:italic>\n                    as a source of antioxidant and enzyme\u2010inhibitory constituents, while structural confirmation and dose\u2010response studies remain necessary.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71625","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:53:37Z","timestamp":1787680417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Online HPLC\u2010Guided Screening of Chemical Composition and Bioactivity in\n                    <i>Capparis ovata<\/i>\n                    subsp.\n                    <i>canescens<\/i>"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6548-7823","authenticated-orcid":false,"given":"Gokhan","family":"Zengin","sequence":"first","affiliation":[{"name":"Department of Biology, Science Faculty Selcuk University  Konya T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shakeel","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Biology, Science Faculty Selcuk University  Konya T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Senkardes","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany Pharmacy Faculty Marmara University  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7192-4962","authenticated-orcid":false,"given":"Milena","family":"Terzic","sequence":"additional","affiliation":[{"name":"Faculty of Technology Novi Sad University of Novi Sad  Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4449-0537","authenticated-orcid":false,"given":"Ozan Emre","family":"Eyupoglu","sequence":"additional","affiliation":[{"name":"School of Pharmacy Department of Biochemistry Istanbul Medipol University  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9600-3526","authenticated-orcid":false,"given":"Sakina","family":"Yagi","sequence":"additional","affiliation":[{"name":"Department of Biology University of Khartoum  Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2025.2494637"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202502727"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2020.1814356"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30183705"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.04.011"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms12128846"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfpp.16286"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5650\/jos.ess24204"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.12991\/jrespharm.1675547"},{"key":"e_1_2_10_11_1","first-page":"63","article-title":"Medicinal Plants Used to Relieve Toothache in Iranian Traditional Medicine","volume":"12","author":"Sadeghi H. 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