{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:09:03Z","timestamp":1788858543682,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260751"],"award-info":[{"award-number":["82260751"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82160824"],"award-info":[{"award-number":["82160824"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In this paper, liquid chromatography coupled with tandem mass spectrometry, utilizing diagnostic product ions and neutral loss techniques, reveals the different chemical composition of fresh\n                    <jats:italic>Taraxacum mongolicum<\/jats:italic>\n                    Hand.\u2010Mazz leaves (TML) treated with three methods: juice, boiled in water for drinking, dried and then boiled for drinking. Additionally, cytotoxicity of fresh TML treated with three methods and the main compounds of TML to KYSE\u2010150 cells were detected. A total of 81 chemical components (including seven authentic standards) were preliminarily identified in fresh TML, including 14 fatty acids, 27 flavonoids, 24 organic acids, 7 iridoid glycosides, and 9 other components. Fatty acids were predominantly present in the fresh TML juice, while other types of compounds were primarily found in the boiling water extract of fresh or dried TML. Furthermore, the boiling water extract of both fresh and dried TML has significant cytotoxicity. In contrast, juice extract of fresh TML did not show significant cytotoxicity. Among these compounds, luteolin from the boiling water extract of fresh or dried TML exhibited the highest cytotoxicity.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71629","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:07:06Z","timestamp":1787753226000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Processing Methods on the Chemical Composition and Cytotoxicity Against Esophageal Cancer Cells of Fresh\n                    <i>Taraxacum mongolicum<\/i>\n                    Hand.\u2010Mazz. Leaves"],"prefix":"10.1002","volume":"23","author":[{"given":"Xiaomin","family":"Huang","sequence":"first","affiliation":[{"name":"The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine Jiangxi University of Chinese Medicine  Nanchang Jiangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8105-5422","authenticated-orcid":false,"given":"Ting","family":"Tan","sequence":"additional","affiliation":[{"name":"The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine Jiangxi University of Chinese Medicine  Nanchang Jiangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5143-5918","authenticated-orcid":false,"given":"Yun","family":"Luo","sequence":"additional","affiliation":[{"name":"Key Laboratory of Modern Preparation of Traditional Chinese Medicine Ministry of Education Jiangxi University of Chinese Medicine  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm16060317"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864\u2010025\u201001308\u20106"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.70934"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.131380"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.13422\/j.cnki.syfjx.20220826"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/15347354211061720"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13121449"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117334"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbp.2023.09.005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15194120"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.70225"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.19540\/j.cnki.cjcmm.20241031.301"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.10134"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.8527"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.202200323"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.02.041"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2019.02.027"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2022.114595"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2018.02.037"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201801212"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b05588"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2024.5401"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.2869"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2021.05.003"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71629","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.71629","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.71629","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:27:33Z","timestamp":1788856053000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.71629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":24,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/cbdv.71629"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.71629","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71629"}}