{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:56:29Z","timestamp":1790546189979,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Lippia alba<\/jats:italic>\n                    (Verbenaceae) is a native Brazilian medicinal species with varied applications, notable for the diversity of volatile chemotypes defined by the major compounds of its essential oil, with fewer studies of its nonvolatile composition. The objective of this work was to perform the chemical characterization via GC\u2010MS and LC\u2010MS of five\n                    <jats:italic>L. alba<\/jats:italic>\n                    individuals, collected during the rainy and dry season. The chromatographic results were analyzed via untargeted metabolomics. Four of the five individuals maintained the same major essential oil composition between the two periods evaluated and each volatile chemotype presented distinct major compounds. The nonvolatile composition, however, was similar for the five\n                    <jats:italic>L. alba<\/jats:italic>\n                    individuals. Some volatile and nonvolatile compounds varied between seasons, demonstrating a discrete effect of the environment on their chemical composition. These results are fundamental for the medicinal application and quality control of this species.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71664","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:33:45Z","timestamp":1788201225000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seasonal Effect on the Chemical Composition of\n                    <i>Lippia alba<\/i>\n                    Volatile Chemotypes"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0152-9219","authenticated-orcid":false,"given":"Marcelino Santiago","family":"Barroso Neto","sequence":"first","affiliation":[{"name":"Institute of Biology State University of Campinas  Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5896-6689","authenticated-orcid":false,"given":"Erilene Nayr\u00e3 Mendon\u00e7a Brito","family":"Lopes","sequence":"additional","affiliation":[{"name":"Institute of Biology State University of Campinas  Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8270-4308","authenticated-orcid":false,"given":"Marcia Ortiz Mayo","family":"Marques","sequence":"additional","affiliation":[{"name":"Agronomic Institute (IAC) Plant Genetic Resources Center (Phytochemistry)  Campinas SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6400-5201","authenticated-orcid":false,"given":"Alex Aparecido Rosini","family":"Silva","sequence":"additional","affiliation":[{"name":"Laboratory of Mass Spectrometry MS4Life S\u00e3o Francisco University  Bragan\u00e7a Paulista SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2681-7022","authenticated-orcid":false,"given":"Patricia de Oliveira","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Laboratory of Mass Spectrometry MS4Life S\u00e3o Francisco University  Bragan\u00e7a Paulista SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7524-6628","authenticated-orcid":false,"given":"Alexandra Christine Helena Frankland","family":"Sawaya","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Science State University of Campinas  Campinas SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pestbp.2021.104901"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/87559129.2021.1900230"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2022.103303"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2021.100527"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0335519"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-40422007000200026"},{"key":"e_1_2_9_8_1","volume-title":"Bot\u00e2nica Sistem\u00e1tica: Guia para Identifica\u00e7\u00e3o das Fam\u00edlias de Faner\u00f3gamas Nativas e Ex\u00f3ticas no Brasil, Baseado em APG IV","author":"Souza V. 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