{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:58:06Z","timestamp":1790542686739,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22177143"],"award-info":[{"award-number":["22177143"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Marine microorganisms represent a prolific reservoir of chemically diverse natural products endowed with considerable therapeutic potential. In the present study, two new asperfurans (\n                    <jats:bold>1<\/jats:bold>\n                    and\n                    <jats:bold>2<\/jats:bold>\n                    ) and 23 known compounds (\n                    <jats:bold>3<\/jats:bold>\n                    \u2013\n                    <jats:bold>25<\/jats:bold>\n                    ) were obtained from\n                    <jats:italic>Aspergillus flavus<\/jats:italic>\n                    , a marine fungus isolated from a water sample of the Western Pacific. Their structures were determined by detailed analysis of the 1D and 2D NMR, HRESIMS, and NMR calculations with DP4+ probability analysis, as well as ECD calculations. Asperfuran (\n                    <jats:bold>3<\/jats:bold>\n                    ) exhibited potent inhibitory activity against renin\u2010angiotensin system\u2010selective lethal 3 (RSL3)\u2010induced ferroptosis with a half maximal effective concentration (EC\n                    <jats:sub>50<\/jats:sub>\n                    ) value of 0.81 \u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71713","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:55:26Z","timestamp":1789469726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine\u2010Derived Fungus\n                    <i>Aspergillus 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