{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:56:24Z","timestamp":1790546184600,"version":"4.1.0"},"reference-count":66,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study comparatively evaluated the phytochemical composition and bioactivities of methanolic extracts and aqueous decoctions obtained from seeds of two Fabaceae taxa (\n                    <jats:italic>Gonocytisus angulatus<\/jats:italic>\n                    ,\n                    <jats:italic>Podocytisus caramanicus<\/jats:italic>\n                    ). Aqueous decoction yielded higher extraction efficiencies (up to 39.20%), whereas methanolic extraction recovered a broader range of phenolic compounds. Phytochemical analysis revealed that flavonoids and phenolic acids were the dominant constituents, with chlorogenic acid, rutin, quercetin, kaempferol, and gallic acid as the major compounds, particularly enriched in methanolic extracts. In vitro assays demonstrated moderate enzyme inhibitory effects. The highest \u03b1\u2010glucosidase inhibition was observed in the methanolic extract (20.22%), while \u03b1\u2010amylase inhibition reached 30.11%. Anticholinesterase activity was also weak, with maximum acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition values of 15.27% and 19.93%, respectively. In contrast, antioxidant activity was more pronounced, with ABTS radical scavenging reaching 97.40%, comparable to the reference standard. Molecular docking supported these findings by indicating favorable binding interactions of major phenolic compounds with target enzymes.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71739","type":"journal-article","created":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T19:48:45Z","timestamp":1790538525000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bio\u2010Based Potential of Phenolic\u2010Rich Fabaceae Seeds (\n                    <i>Gonocytisus angulatus, Podocytisus caramanicus<\/i>\n                    ): Chemical Standardization, Functional Screening, and Molecular Insights"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6550-6916","authenticated-orcid":false,"given":"Burak","family":"Bayrak","sequence":"first","affiliation":[{"name":"Department of Analytical Chemistry Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferhat","family":"G\u00fcne\u015f","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8748-790X","authenticated-orcid":false,"given":"Beyzanur","family":"Aky\u00fcz","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7484-1126","authenticated-orcid":false,"given":"Elif","family":"Beyza \u00d6zer","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Ondokuz May\u0131s University  Samsun T\u00fcrkiye"},{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amenah Imad","family":"Abdulqader","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"\u00c7iva\u015f","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"},{"name":"Department of Pharmacy Services, Tuzluca Vocational School Igd\u0131r University  Igd\u0131r T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130sranur","family":"K\u00fc\u00e7\u00fcksu","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice R\u00fcmeysa","family":"S\u00f6nmez","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"},{"name":"Department of Pharmacognosy Faculty of Pharmacy A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  A\u011fr\u0131 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1315-9876","authenticated-orcid":false,"given":"\u00d6mer","family":"\u00c7e\u00e7en","sequence":"additional","affiliation":[{"name":"Department of Biology Kamil \u00d6zda\u011f Faculty of Science Karamano\u011flu Mehmetbey University  Karaman T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Erzincan Binali Y\u0131ld\u0131r\u0131m University  Erzincan T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-8988","authenticated-orcid":false,"given":"Furkan","family":"\u00c7oban","sequence":"additional","affiliation":[{"name":"Department of Field Crops Faculty of Agriculture Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0857-4776","authenticated-orcid":false,"given":"Hafize","family":"Yuca","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3268-721X","authenticated-orcid":false,"given":"Song\u00fcl","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany Faculty of Pharmacy Atat\u00fcrk University  Erzurum 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