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The confrontation assay demonstrated that both\n                    <jats:italic>I. lacteus<\/jats:italic>\n                    YICB\u20100055 and\n                    <jats:italic>I. laceratus<\/jats:italic>\n                    YICB\u20100007 exhibit inhibitory effects against\n                    <jats:italic>Fusarium oxysporum<\/jats:italic>\n                    YICB\u20100025 under light exposure with cAMP supplementation. HPLC analysis revealed a rich metabolite fingerprint under continuous light exposure in the presence of 5\u00a0mM cAMP. Chemical investigation of the optimized fermentation afforded two new tremulane\u2010type sesquiterpenes, ceriponols N\u2013O (\n                    <jats:bold>1<\/jats:bold>\n                    and\n                    <jats:bold>2<\/jats:bold>\n                    ), together with eight known compounds (\n                    <jats:bold>3<\/jats:bold>\n                    \u2013\n                    <jats:bold>10<\/jats:bold>\n                    ), all of which were structurally characterized by extensive spectroscopic analyses. These compounds exhibited antifungal activity against plant\u2010pathogenic fungi such as\n                    <jats:italic>F. oxysporum<\/jats:italic>\n                    . The results suggest that cAMP supplementation combined with light exposure may enhance secondary metabolite production in\n                    <jats:italic>Irpex<\/jats:italic>\n                    fungi, indicating their potential as sources of antimicrobial compounds.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71754","type":"journal-article","created":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:22:28Z","timestamp":1790540548000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two New Tremulane\u2010Type Sesquiterpenes From\n                    <i>Irpex lacteus<\/i>\n                    Cultured Under Optimized cAMP and Light Conditions"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3587-5969","authenticated-orcid":false,"given":"Rui","family":"Guo","sequence":"first","affiliation":[{"name":"Yantai Institute of Coastal Zone Research Chinese Academy of Sciences  Yantai People's Republic of China"},{"name":"University of Chinese Academy of Sciences  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6526-4731","authenticated-orcid":false,"given":"Naiyun","family":"Ji","sequence":"additional","affiliation":[{"name":"Yantai Institute of Coastal Zone Research Chinese Academy of Sciences  Yantai People's Republic of China"},{"name":"University of Chinese Academy of Sciences  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1701.01036"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105165"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof8090913"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1155888"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/21623945.2025.2603605"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13068\u2010021\u201001914\u20100"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002030050659"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/cimb44060179"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13062"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010genet\u2010120417\u2010031415"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13225\u2010016\u20100358\u20109"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/md16070244"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2021.104983"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.105223"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13369\u2010025\u201010258\u2010y"},{"key":"e_1_2_10_17_1","first-page":"2183","article-title":"Cytotoxic Compounds From the Marine Actinomycete Streptomyces sp. 124092","volume":"11","author":"Xie X. 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